1-Chloro-2-fluoro-3-(2-methoxy-4-nitrobenzyl)benzene CAS 1427501-84-5
| CAS No. | 1427501-84-5 |
| Molecular Formula | C14H11ClFNO3 |
| Molecular Weight | 295.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-Chloro-2-fluoro-3-(2-methoxy-4-nitrobenzyl)benzene (C14H11ClFNO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
1-Chloro-2-fluoro-3-(2-methoxy-4-nitrobenzyl)benzene (CAS 1427501-84-5), molecular formula C14H11ClFNO3 and molecular weight 295.69 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-Chloro-2-fluoro-3-(2-methoxy-4-nitrobenzyl)benzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H11ClFNO3 |
| Molecular Weight | 295.69 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
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Recommended Standards
- Tert-butyl 2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)acetate (CAS 1672655-80-9)
- Tert-butyl (2-chloro-5-(trifluoromethyl)phenyl)carbamate (CAS 1260834-16-9)
- 3-Methyl-5-(2,2,2-trifluoroethoxy)isothiazole-4-sulfonyl chloride (CAS 111923-86-5)
- 4-Cyano-2-difluoromethoxy-6-ethylbenzenesulfonyl chloride (CAS 1807157-43-2)
- 7-Methoxyisoquinolin-8-amine (CAS 55766-74-0)
- Propionylcarnitine (CAS 17298-37-2)
- Methyl 4-formyltetrahydro-2H-pyran-4-carboxylate (CAS 907607-89-0)
- 4-Chloro-1H-indazole-3-carbonitrile (CAS 1264481-55-1)
- 3-(5-Amino-1,3,4-oxadiazol-2-yl)benzenesulfonamide (CAS 62036-00-4)
- 3-(2,4-dioxohexahydropyrimidin-1-yl)-4-fluoro-benzoic acid (CAS 2377643-38-2)
- 2-(1,4-Diazepan-1-yl)acetonitrile (CAS 157341-35-0)
- 4'-Chloro-[1,1'-biphenyl]-2,3'-dicarboxylic acid 2-methyl ester (CAS 878207-35-3)
- (2E)-N-(Adamantan-1-yl)-2-phenyl-3-(thiophen-2-yl)prop-2-enamide (CAS 478078-59-0)
- Semaglutide Impurity 150 xTFA (CAS CATO-C4X-2226150)
Why CATO?
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