N4-(2-Chlorophenyl)quinazoline-4,6-diamine CAS 1428063-70-0
| CAS No. | 1428063-70-0 |
| Molecular Formula | C14H11ClN4 |
| Molecular Weight | 270.72 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of N4-(2-Chlorophenyl)quinazoline-4,6-diamine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
N4-(2-Chlorophenyl)quinazoline-4,6-diamine (CAS 1428063-70-0) is a high-purity analytical reference standard with the molecular formula C14H11ClN4 and a molecular weight of 270.72 g/mol.
The molecular framework of N4-(2-Chlorophenyl)quinazoline-4,6-diamine (C14H11ClN4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), N4-(2-Chlorophenyl)quinazoline-4,6-diamine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H11ClN4 |
| Molecular Weight | 270.72 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
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Recommended Standards
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- 4-Chloro-3-(3-methyl-2,5-dioxo-3-phenylpyrrolidin-1-yl)benzenesulfonamide (CAS 30279-22-2)
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- 4-((4-(3-Chlorophenyl)piperazin-1-yl)methyl)-6-ethyl-2H-chromen-2-one hydrochloride (CAS 1177436-90-6)
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- 4-Bromo-2-nitro-1-phenylbenzene (CAS 70873-41-5)
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- 2,4-diphenylbut-3-yn-2-ol (CAS 5876-69-7)
- Tirzepatide Impurity 18 (CAS CATO-C4X-324018)
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