4-(Hydroxymethyl)thiophene-2-carboxylic acid CAS 14282-65-6
| CAS No. | 14282-65-6 |
| Molecular Formula | C6H6O3S |
| Molecular Weight | 158.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(Hydroxymethyl)thiophene-2-carboxylic acid (C6H6O3S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
4-(Hydroxymethyl)thiophene-2-carboxylic acid (CAS 14282-65-6), molecular formula C6H6O3S and molecular weight 158.18 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-(Hydroxymethyl)thiophene-2-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H6O3S |
| Molecular Weight | 158.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Sulfur Atoms | 1 |
Related Hydroxymethyl Standards
- 5-(Hydroxymethyl)thiophene-2-carboxylic acid (CAS 14282-64-5)
- 5-(Hydroxymethyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (CAS 93185-31-0)
- 5-(Hydroxymethyl)thiophene-3-carboxylic acid (CAS 25744-99-4)
- 6-(Hydroxymethyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (CAS 31555-11-0)
- Methyl 2-(3-(hydroxymethyl)cyclobutyl)acetate (CAS 1114554-24-3)
- Ethyl 1-(hydroxymethyl)cyclobutane-1-carboxylate (CAS 1195-81-9)
- 3-(Hydroxymethyl)cyclohexane-1-carboxylic acid (CAS 13380-83-1)
- 4-(Hydroxymethyl)cyclohexanecarboxylic Acid (cis- and trans- mixture) (CAS 13380-84-2)
Recommended Standards
- 2-(sulfanylmethyl)furan-3-carboxylic acid (CAS 143723-08-4)
- 4-(Methylsulfonyl)pyrimidine (CAS 14161-10-5)
- 3-(sulfanylmethyl)furan-2-carboxylic acid (CAS 143723-09-5)
- 2-Methanesulfonyl-pyrimidine (CAS 14161-09-2)
- 1-{[3-(2,5-dichlorophenoxy)-2-hydroxypropyl]amino}propan-2-ol (CAS 784159-73-5)
- 1-(2-(Benzylthio)-4,5-dihydro-1H-imidazol-1-yl)-2-phenoxypropan-1-one (CAS 851864-28-3)
- (S)-1-(6-Iodopyridin-3-yl)ethan-1-amine (CAS 1213176-61-4)
- 1-tert-Butyl-3-azetidinol (CAS 13156-04-2)
- 3-(Cyclopentyloxy)-2-methylaniline (CAS 1154909-64-4)
- 2-fluoro-4,6-dimethylaniline (CAS 1780776-35-3)
- N,N-diethyl-2-(4-(2-(2-fluorophenyl)-1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy)ethan-1-amine 2-hydroxypropane-1,2,3-tricarboxylate(1:x) (CAS 13754-17-1)
- 4-(7-Oxooctahydroindolizin-6-yl)phenyl acetate (CAS 111751-99-6)
- 2-Amino-N-(2,5-difluorophenyl)acetamide (CAS 1016800-19-3)
- Semaglutide Impurity 18 (CAS 1671100-14-3)
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