Ethyl 5-(bromomethyl)thiophene-2-carboxylate CAS 14282-72-5

Purity 97%+In StockPharmaceutical Standards
CAS No.14282-72-5
Molecular FormulaC8H9BrO2S
Molecular Weight249.12 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Ethyl 5-(bromomethyl)thiophene-2-carboxylate CAS 14282-72-5 chemical structure

Description

The occurrence of Ethyl 5-(bromomethyl)thiophene-2-carboxylate is closely related to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies Ethyl 5-(bromomethyl)thiophene-2-carboxylate (CAS 14282-72-5), a certified reference material (molecular formula C8H9BrO2S, MW 249.12 g/mol) for analytical method development and quality control.

The molecular framework of Ethyl 5-(bromomethyl)thiophene-2-carboxylate (C8H9BrO2S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), Ethyl 5-(bromomethyl)thiophene-2-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H9BrO2S
Molecular Weight249.12 g/mol
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1961
Halogen ContentBr-containing
Sulfur Atoms1

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