6-Bromo-3-(difluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine CAS 1428532-79-9

Purity 97%+In StockPharmaceutical Standards
CAS No.1428532-79-9
Molecular FormulaC7H4BrF2N3
Molecular Weight248.03 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-Bromo-3-(difluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine CAS 1428532-79-9 chemical structure

Description

The occurrence of 6-Bromo-3-(difluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine is closely related to a nitrile group, fluorine/bromine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 6-Bromo-3-(difluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine (CAS 1428532-79-9), a certified reference material (molecular formula C7H4BrF2N3, MW 248.03 g/mol) for analytical method development and quality control.

The molecular framework of 6-Bromo-3-(difluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine (C7H4BrF2N3) is characterized by a nitrile group, fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC7H4BrF2N3
Molecular Weight248.03 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Halogen ContentF/Br-containing
Nitrogen Atoms3

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