8-Chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-ol CAS 1428532-93-7
| CAS No. | 1428532-93-7 |
| Molecular Formula | C7H3ClF3N3O |
| Molecular Weight | 237.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 237.57 g/mol gives 8-Chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-ol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
8-Chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-ol (CAS 1428532-93-7) is a high-purity analytical reference standard with the molecular formula C7H3ClF3N3O and a molecular weight of 237.57 g/mol.
The molecular framework of 8-Chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-ol (C7H3ClF3N3O) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 8-Chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-ol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H3ClF3N3O |
| Molecular Weight | 237.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 6-Chloro-1-Hydroxy-2-(Trifluoromethyl)Imidazo[4,5-b]Pyridine (CAS 35195-95-0)
- 2-Chloro-5-(trifluoromethoxy)benzo[d]oxazole (CAS 1198792-80-1)
- 2-Chloro-4-isocyanato-1-(trifluoromethoxy)benzene (CAS 40275-96-5)
- 2-(3-Chloro-2-fluoro-4-(trifluoromethyl)phenyl)acetonitrile (CAS 1431329-60-0)
- 2-(4-Chloro-3-fluoro-5-(trifluoromethyl)phenyl)acetonitrile (CAS 1431329-62-2)
- 2-(3-Chloro-2-fluoro-5-(trifluoromethyl)phenyl)acetonitrile (CAS 261763-15-9)
- 2-(3-Chloro-2-fluoro-6-(trifluoromethyl)phenyl)acetonitrile (CAS 261763-16-0)
- 2-(2-Chloro-6-(difluoromethoxy)pyridin-4-yl)acetic acid (CAS 1227578-91-7)
Recommended Standards
- 2-Amino-5-chloro-3-(trifluoromethoxy)isonicotinonitrile (CAS 1803920-71-9)
- 4-Amino-6-chloro-5-(trifluoromethoxy)picolinonitrile (CAS 1804013-44-2)
- 1,3,5-Trimethyl-2-(trichloromethyl)benzene (CAS 707-74-4)
- 1,2-Dichloro-4-(1-chlorobutyl)benzene (CAS 68120-77-4)
- 5-(Methylsulfonyl)-4-(p-tolyl)-1H-thieno[2,3-c]pyrazol-3-amine (CAS 1708269-27-5)
- 7-Methyl-[1,2,4]triazolo[4,3-a]pyridine (CAS 4919-10-2)
- 2-(Benzyloxy)-5-bromo-1,3-difluorobenzene (CAS 99045-18-8)
- 3-(1-Methyl-1H-imidazol-2-ylmethyl)-piperidine dihydrochloride (CAS 1361115-17-4)
- 2-(4-(Difluoromethyl)-5-methoxy-6-(trifluoromethyl)pyridin-2-yl)acetic acid (CAS 1805266-42-5)
- Vonoprazan Impurity 64 (CAS 928324-73-6)
- 2-Amino-N-ethyl-N-(1-methyl-pyrrolidin-3-ylmethyl)-acetamide (CAS 1353976-90-5)
- 2,2,3,3-Tetrafluoro-2,3-dihydrobenzo[b][1,4]dioxine-6-carboxylic acid (CAS 180091-38-7)
- 2,6-Dibromo-4-isopropylaniline (CAS 10546-65-3)
- [D-Ser8]-Semaglutide A (CAS CATO-C4X-2226116)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com