Tert-butyl (3S,4R)-3-amino-4-(trifluoromethyl)pyrrolidine-1-carboxylate CAS 1428776-57-1
| CAS No. | 1428776-57-1 |
| Molecular Formula | C10H17F3N2O2 |
| Molecular Weight | 254.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Tert-butyl (3S,4R)-3-amino-4-(trifluoromethyl)pyrrolidine-1-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Tert-butyl (3S,4R)-3-amino-4-(trifluoromethyl)pyrrolidine-1-carboxylate (CAS 1428776-57-1) is a high-purity analytical reference standard with the molecular formula C10H17F3N2O2 and a molecular weight of 254.25 g/mol.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, Tert-butyl (3S,4R)-3-amino-4-(trifluoromethyl)pyrrolidine-1-carboxylate is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 254.25 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H17F3N2O2 |
| Molecular Weight | 254.25 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- (3R,4S)-tert-Butyl 3-Amino-4-(trifluoromethyl)pyrrolidine-1-carboxylate (CAS 1428776-56-0)
- Ethyl 2-(4-fluoro-3-propoxyphenyl)-2-oxoacetate (CAS 1443310-50-6)
- tert-Butyl 4-(trifluoromethyl)piperazine-1-carboxylate (CAS 1415564-92-9)
- Ethyl 2-(4-fluoro-2-propoxyphenyl)-2-oxoacetate (CAS 1443334-49-3)
- 5-MeO-MET (CAS 16977-53-0)
- Ethyl 4-bromo-2-cyano-5-iodobenzoate (CAS 1805183-75-8)
- 2-(4-Chlorophenyl)-2,3-dihydro-1H-naphtho[1,8-de][1,3,2]diazaborinine (CAS 1336918-65-0)
- 2-(4-Benzylmorpholin-3-yl)acetonitrile (CAS 170701-93-6)
- {3-[(4-fluorophenyl)methyl]-1,2,4-oxadiazol-5-yl}methanol (CAS 1341975-18-5)
- Boc-Dab-OtBu · HCl (CAS 190447-69-9)
- N-(5,5-Dimethyl-2-oxotetrahydrofuran-3-yl)-5-nitrofuran-3-carboxamide (CAS 101833-02-7)
- tert-Butyl 3-bromo-4-chlorophenylcarbamate (CAS 1080573-26-7)
- 3-Methyl-3-phenylcyclobutan-1-amine (CAS 1258826-70-8)
- Des-Pro36-Tirzepatide (CAS CATO-CPTD788937)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com