2-Cyclohexyl-2,2-difluoroacetic acid CAS 142977-61-5
| CAS No. | 142977-61-5 |
| Molecular Formula | C8H12F2O2 |
| Molecular Weight | 178.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 178.18 g/mol gives 2-Cyclohexyl-2,2-difluoroacetic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-Cyclohexyl-2,2-difluoroacetic acid (CAS 142977-61-5) is a high-purity analytical reference standard with the molecular formula C8H12F2O2 and a molecular weight of 178.18 g/mol.
Structurally, 2-Cyclohexyl-2,2-difluoroacetic acid (C8H12F2O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 2.0, corresponding to approximately 2 ring(s) or double-bond equivalent(s). With a molecular weight of 178.18 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Cyclohexyl-2,2-difluoroacetic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H12F2O2 |
| Molecular Weight | 178.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F-containing |
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- Methyl 2-(3-formylphenyl)acetate (CAS 142327-44-4)
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- 2-(4-Ethoxyphenyl)-2-oxoacetaldehyde (CAS 14333-52-9)
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- 1-(2-Fluorophenyl)hexan-2-one (CAS 150322-71-7)
- 1-chloroethane-1-sulfonamide (CAS 23915-18-6)
- 2-Chloro-n-(3-ethoxypropyl)acetamide (CAS 10263-65-7)
- n-(1-Benzylpyrrolidin-3-yl)-2-chloropropanamide hydrochloride (CAS 1210664-95-1)
- 2-((3-Chlorophenyl)amino)benzamide (CAS 13625-33-7)
- (R)-2-(Pyridin-2-yl)but-3-yn-2-ol (CAS 1233718-06-3)
- Cefbuperazone Sodium (CAS 76648-01-6)
- Tau Peptide (74-102) (Exon 3/Insert 2 Domain) trifluoroacetate salt (CAS 1322695-34-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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