Clopidogrel Impurity 51 CAS 1430373-14-0
| CAS No. | 1430373-14-0 |
| Molecular Formula | C25H26ClNO6S |
| Molecular Weight | 504.00 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Clopidogrel Impurity 51 (C25H26ClNO6S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Clopidogrel Impurity 51 (CAS 1430373-14-0) is a certified pharmaceutical impurity reference standard with the molecular formula C25H26ClNO6S and a molecular weight of 504.00 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Clopidogrel Impurity 51 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H26ClNO6S |
| Molecular Weight | 504.00 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Clopidogrel Standards
- Clopidogrel Impurity 6 (CAS 1346598-12-6)
- Clopidogrel Metabolite II (Mixture of Diastereomers) (CAS 1287430-40-3)
- Clopidogrel Impurity 52 (CAS 1430373-12-8)
- Clopidogrel Impurity 89 (CAS CATO-C4X-102989)
- Clopidogrel Impurity 92 (CAS CATO-C4X-102992)
- rac-Clopidogrel-MP Endo Derivative-13C,d3 (CAS 1346597-76-9)
- Clopidogrel Impurity 92-13C,d3 (CAS CATO-C4X-1029129)
- cis-Clopidogrel-MP Derivative 13CD3 (CAS CATO-C4X-102966)
Recommended Standards
- Dasatinib Impurity 12 (CAS 910297-57-3)
- CCT-251455, >98% (HPLC) (CAS 1400284-80-1)
- Dasatinib Impurity 15 (CAS 910297-58-4)
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- Ixazomib Impurity 26 (CAS CATO-C4X-126726)
- Cholic Acid Impurity 14 (CAS CATO-C4X-116014)
- Oxazepam impurity 02 (CAS 4015-28-5)
- 3-Amino-N-(pyridin-3-ylmethyl)propanamide hydrochloride (CAS 1208947-75-4)
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- 2-Methyl-2-phenylcyclopropan-1-amine (CAS 19009-66-6)
- 2-(2-Bromoethoxy)-1,3-dichlorobenzene (CAS 26583-73-3)
- (S)-2-phenylaziridine (CAS 25260-42-8)
- Biotinyl-Glucagon (1-29) (human, rat, porcine) trifluoroacetate salt (CAS 1802086-28-7)
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