Cefaclor EP Impurity C CAS 143059-69-2
| CAS No. | 143059-69-2 |
| Molecular Formula | C15H14ClN3O4S |
| Molecular Weight | 367.81 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Cefaclor EP Impurity C (CAS 143059-69-2) is a certified pharmaceutical impurity reference standard with the molecular formula C15H14ClN3O4S and a molecular weight of 367.81 g/mol.
Structurally, Cefaclor EP Impurity C (C15H14ClN3O4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 367.81 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H14ClN3O4S |
| Molecular Weight | 367.81 g/mol |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Cefaclor Standards
- Cefaclor (CAS 53994-73-3)
- Cefaclor Impurity 15 (CAS CATO-C4X-127015)
- Cefaclor EP Impurity D (Mixture of Diastereomers) (CAS 152575-13-8)
- Cefaclor Diketopiperazine (CAS CATO-C4X-127051)
- Cefaclor Impurity 54 (CAS CATO-C4X-127054)
- Cefaclor Impurity 64 (CAS CATO-C4X-127064)
- Cefaclor Impurity C37 (CAS 53994-83-5)
- Cefaclor Impurity 23 (CAS 1426173-90-1)
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