(R)-N-(1-(naphthalen-1-yl)ethyl)-3-(2-(trifluoromethyl)phenyl)propan-1-amine CAS 1431699-53-4
| CAS No. | 1431699-53-4 |
| Molecular Formula | C22H22F3N |
| Molecular Weight | 357.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(R)-N-(1-(naphthalen-1-yl)ethyl)-3-(2-(trifluoromethyl)phenyl)propan-1-amine (CAS 1431699-53-4) is a high-purity analytical reference standard with the molecular formula C22H22F3N and a molecular weight of 357.41 g/mol.
(R)-N-(1-(naphthalen-1-yl)ethyl)-3-(2-(trifluoromethyl)phenyl)propan-1-amine (C22H22F3N) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (R)-N-(1-(naphthalen-1-yl)ethyl)-3-(2-(trifluoromethyl)phenyl)propan-1-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H22F3N |
| Molecular Weight | 357.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- (R)-Methyl-N-[3-[4-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethan amine (CAS 1428185-71-0)
- (R)-2-((5-(3-Methyl-1H-indazol-5-yl)pyridin-3-yl)amino)-2-phenylacetamide (CAS 1613639-20-5)
- APD 371 (CAS 1268881-20-4)
- (S)-N-(1-(Naphthalen-2-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine (CAS 1638501-43-5)
- Tetraethyl butane-1,2,2,4-tetracarboxylate (CAS 70600-48-5)
- 2-(2-Hydroxy-2-methylpropyl)cyclohexan-1-ol (CAS 91008-63-8)
- Tert-butyl 3-(((2-fluorobenzyl)amino)methyl)azetidine-1-carboxylate (CAS 887590-08-1)
- 3,4-DICARBOXYTHIOPHENE 3,4-THIOPHENEDICARBOXYLIC ACID 4282-29-5 AS06782 Thiophene-3,4-dicarboxylic acid (CAS 4282-29-5)
- Epoxomicin (CAS 134381-21-8)
- 5-Hydroxy-6-methylnicotinonitrile (CAS 3307-82-2)
- 6-methylnaphthalene-2-sulfonamide (CAS 215958-81-9)
- DFHBI 1T (CAS 1539318-36-9)
- Ethyl 9H-pyrido[3,4-b]indole-1-carboxylate (CAS 72755-19-2)
- Des-Ile27-Tirzepatide (CAS CATO-CPTD788946)
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