2-(2-Chlorophenyl)-5-(trifluoromethyl)-2H-1,2,3-triazole-4-carboxylic acid CAS 1431727-78-4
| CAS No. | 1431727-78-4 |
| Molecular Formula | C10H5ClF3N3O2 |
| Molecular Weight | 291.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(2-Chlorophenyl)-5-(trifluoromethyl)-2H-1,2,3-triazole-4-carboxylic acid.
CATO supplies 2-(2-Chlorophenyl)-5-(trifluoromethyl)-2H-1,2,3-triazole-4-carboxylic acid (CAS 1431727-78-4), a certified reference material (molecular formula C10H5ClF3N3O2, MW 291.61 g/mol) for analytical method development and quality control.
The molecular framework of 2-(2-Chlorophenyl)-5-(trifluoromethyl)-2H-1,2,3-triazole-4-carboxylic acid (C10H5ClF3N3O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(2-Chlorophenyl)-5-(trifluoromethyl)-2H-1,2,3-triazole-4-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H5ClF3N3O2 |
| Molecular Weight | 291.61 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chlorophenyl Standards
- 3-(4-Chlorophenyl)-5-(trifluoromethyl)isoxazole-4-carboxylic Acid (CAS 1159978-81-0)
- 2-(4-Chlorophenyl)-5-(trifluoromethyl)-2H-1,2,3-triazole-4-carboxylic acid (CAS 1707584-27-7)
- 6-(4-Chlorophenyl)-3-(methoxycarbonyl)picolinic acid (CAS 1443288-37-6)
- 3-(4-Chlorophenyl)-5,7-dimethylisoxazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione (CAS 68205-95-8)
- 6-(3-(4-Chlorophenyl)ureido)pyridazine-3-carboxamide (CAS 87977-06-8)
- N'-(4-chlorophenyl)-N-hydroxy-3-nitrobenzimidamide (CAS 692287-17-5)
- 2-((2-((2-Chlorophenyl)amino)-2-oxoethyl)sulfonyl)acetic acid (CAS 344267-76-1)
- 2-((2-((3-Chlorophenyl)amino)-2-oxoethyl)sulfonyl)acetic acid (CAS 344267-83-0)
Recommended Standards
- 1-((6-Bromohexyl)oxy)-3-chlorobenzene (CAS 130402-57-2)
- 5-Chloro-2-(3-(trifluoromethyl)phenyl)-2H-1,2,3-triazole-4-carboxylic acid (CAS 1431729-06-4)
- 1-(3-Chloropyridin-2-yl)-5-(trifluoromethyl)-1h-pyrazole-4-carboxylic acid (CAS 1265323-81-6)
- 1-(2-Bromo-1-isobutoxyethyl)-4-chlorobenzene (CAS 1251365-21-5)
- 1-Iodo-4-isopropylbenzene (CAS 17356-09-1)
- 2-(Thiophen-2-yl)tetrahydro-2H-pyran-4-amine (CAS 1909309-66-5)
- 2,2-Dimethylheptanoic acid (CAS 14250-73-8)
- 4-((3-Amino-2H-indazol-2-yl)methyl)-N-(2-aminophenyl)benzamide (CAS 920315-49-7)
- 4,5-Bis(2-cyanoethylthio)-1,3-dithiole-2-thione (CAS 132765-35-6)
- Cis-dimethyl cyclohexane-1,2-dicarboxylate (CAS 1687-29-2)
- Pregabalin impurity 01 (CAS 466678-45-5)
- 4,5-Dichloropyridin-3-ol (CAS 1261269-63-9)
- 2-Methyl-5-nitrobenzanilide (CAS 599171-08-1)
- Semaglutide impurity 78 (CAS CATO-C4X-222678)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com