Ethyl 2-(5-chloropyrimidin-2-yl)-5-methyl-2H-1,2,3-triazole-4-carboxylate CAS 1431728-70-9
| CAS No. | 1431728-70-9 |
| Molecular Formula | C10H10ClN5O2 |
| Molecular Weight | 267.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Ethyl 2-(5-chloropyrimidin-2-yl)-5-methyl-2H-1,2,3-triazole-4-carboxylate (C10H10ClN5O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies Ethyl 2-(5-chloropyrimidin-2-yl)-5-methyl-2H-1,2,3-triazole-4-carboxylate (CAS 1431728-70-9), a certified reference material (molecular formula C10H10ClN5O2, MW 267.67 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H10ClN5O2 |
| Molecular Weight | 267.67 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Ethyl Standards
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- N-(2-Chloropyrimidin-5-yl)-3,4-difluorobenzamide (CAS 582323-16-8)
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- 5-(4-Chloropyrimidin-5-yl)-3-(thiophen-3-yl)-1,2,4-oxadiazole (CAS 1370595-20-2)
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Recommended Standards
- 1-(2-Chlorobenzyl)-5-methoxy-1H-1,2,3-triazole-4-carboxylic acid (CAS 1378258-91-3)
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- 3-(2-Chloro-4-methoxyphenyl)-5-methylisoxazole-4-carboxylic acid (CAS 1370419-70-7)
- 1-(3-Chloro-2,5-dimethoxyphenyl)-1h-pyrrole-2,5-dione (CAS 438532-74-2)
- 5-(N-(Pyridin-3-ylmethyl)sulfamoyl)furan-2-carboxylic acid (CAS 1038353-98-8)
- 2-(1-Benzyl-1H-indol-3-yl)-1-methyl-ethylaminehydrochloride (CAS 18394-42-8)
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- 5-(3,5-dimethyl-1H-pyrazol-1-yl)pyridine-2-carboximidamide dihydrochloride (CAS 1909328-03-5)
- 5-Bromo-2-cyano-3-nitrobenzoic acid (CAS 1805597-47-0)
- Thymopoietin II Peptide Fragment (CAS 56795-64-3)
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