Ethyl 2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-2,2-difluoroacetate CAS 1431842-79-3
| CAS No. | 1431842-79-3 |
| Molecular Formula | C10H7ClF5NO2 |
| Molecular Weight | 303.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-2,2-difluoroacetate.
Ethyl 2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-2,2-difluoroacetate (CAS 1431842-79-3) is a high-purity analytical reference standard with the molecular formula C10H7ClF5NO2 and a molecular weight of 303.61 g/mol.
The molecular framework of Ethyl 2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-2,2-difluoroacetate (C10H7ClF5NO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Ethyl 2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-2,2-difluoroacetate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H7ClF5NO2 |
| Molecular Weight | 303.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 5-[(Chloroacetyl)amino]-2,4-dinitrobenzoic acid (CAS 1365963-13-8)
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- 1-(((2-Bromocyclohexyl)oxy)methyl)-2-chlorobenzene (CAS 1248322-25-9)
- 2-Bromo-1-(5-chloro-3-methylbenzo[b]thiophen-2-yl)ethan-1-one (CAS 175203-97-1)
- N-((6-Methoxyquinolin-2-yl)methylene)-4-methylaniline (CAS 89070-55-3)
- tert-Butyl 3-(hydroxymethyl)-6,7-dihydropyrazolo[1,5-a]pyrimidine-4(5H)-carboxylate (CAS 1260876-41-2)
- 2-Amino-5-cyano-N,N,3-trimethylbenzamide (CAS 1191424-28-8)
- 5-Bromo-1H-pyrrolo[2,3-b]pyridin-6-ol (CAS 1190316-82-5)
- N-Desisopropyl Delavirdine (CAS 165133-86-8)
- 4-Benzyl-2-(3-(dimethylamino)propyl)isoquinolin-1(2H)-one (CAS 88561-25-5)
- 5-(3-Bromophenyl)-1,2,4-oxadiazole (CAS 1306606-33-6)
- Dolutegravir Impurity 62 (CAS CATO-C4X-162062)
- 4-Bromo-1-(2-methoxyethyl)pyridin-2(1h)-one (CAS 1936135-61-3)
- Tirzepatide Impurity 23 X TFA Salt (CAS CATO-C4X-324023)
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