4-(3-Methoxyphenyl)-2-(piperazin-1-yl)-6-(trifluoromethyl)pyrimidine dihydrochloride CAS 1431970-11-4
| CAS No. | 1431970-11-4 |
| Molecular Formula | C16H17F3N4O |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-(3-Methoxyphenyl)-2-(piperazin-1-yl)-6-(trifluoromethyl)pyrimidine dihydrochloride is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-(3-Methoxyphenyl)-2-(piperazin-1-yl)-6-(trifluoromethyl)pyrimidine dihydrochloride (CAS 1431970-11-4), molecular formula C16H17F3N4OHCl and molecular weight 374.79 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 4-(3-Methoxyphenyl)-2-(piperazin-1-yl)-6-(trifluoromethyl)pyrimidine dihydrochloride (C16H17F3N4OHCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 374.79 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-(3-Methoxyphenyl)-2-(piperazin-1-yl)-6-(trifluoromethyl)pyrimidine dihydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H17F3N4O 2*HCl |
| Molecular Weight | 374.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Methoxyphenyl Standards
- 3-(3-Methoxyphenyl)isonicotinic acid (CAS 100004-80-6)
- 3-(2-Methoxyphenyl)isonicotinic acid (CAS 100004-81-7)
- 2-(3-Methoxyphenyl)isonicotinic acid (CAS 100004-95-3)
- 2-(3-Methoxyphenyl)benzo[d]thiazole (CAS 10002-44-5)
- 4-(5-(4-Methoxyphenyl)oxazol-2-yl)aniline (CAS 10004-75-8)
- 2-(4-Methoxyphenyl)-6-(methylthio)-4H-thiopyran-4-one (CAS 1000574-20-8)
- Ethyl 2-{[2-(4-methoxyphenyl)-4-oxo-4H-chromen-3-yl]oxy}acetate (CAS 100064-06-0)
- Methyl 5-(2-methoxyphenyl)-1H-pyrrole-2-carboxylate (CAS 1000682-34-7)
Recommended Standards
- Ethyl 2-(1,5-dimethyl-1H-pyrazole-3-carboxamido)-4-methylthiazole-5-carboxylate (CAS 1013772-62-7)
- 2-[(2,6-dimethylpiperidin-1-yl)carbonyl]-4,5-dimethoxyaniline (CAS 953892-79-0)
- 1-Boc-2-Butylpiperazine hydrochloride (CAS 1179359-55-7)
- 3,5-Difluoro-4-Vinylphenol (CAS 293753-16-9)
- 6,9-Dichloro-1,2,3,4-tetrahydroacridine (CAS 5396-25-8)
- (E)-4-(benzo[d]thiazol-2-ylamino)-1,1,1-trifluorobut-3-en-2-one (CAS 478040-77-6)
- 2-Chloro-6-methylbenzoyl Chloride (CAS 89894-44-0)
- 5-Methyl-4-(trifluoromethyl)-1h-imidazole-2-carbaldehyde (CAS 1171125-37-3)
- 2-Ethoxy-4-(3-hydroxybutyl)phenol (CAS 1283091-06-4)
- Semaglutide impurity 39 (CAS CATO-C4X-222639)
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