4-(3-Nitrophenyl)-2-(trifluoromethyl)thiazole CAS 1432053-91-2
| CAS No. | 1432053-91-2 |
| Molecular Formula | C10H5F3N2O2S |
| Molecular Weight | 274.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(3-Nitrophenyl)-2-(trifluoromethyl)thiazole (CAS 1432053-91-2) is a high-purity analytical reference standard with the molecular formula C10H5F3N2O2S and a molecular weight of 274.22 g/mol.
The molecular framework of 4-(3-Nitrophenyl)-2-(trifluoromethyl)thiazole (C10H5F3N2O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-(3-Nitrophenyl)-2-(trifluoromethyl)thiazole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H5F3N2O2S |
| Molecular Weight | 274.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Nitrophenyl Standards
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Recommended Standards
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- 5-Chloro-4-(difluoromethyl)pyridin-2-amine (CAS 1804660-46-5)
- 1-(Trifluoromethyl)cyclobutane-1-sulfinate (sodium) (CAS 2917638-75-4)
- tert-butyl N-{2-[(4-aminobenzene)sulfonamido]ethyl}carbamate (CAS 902775-91-1)
- 2-Bromo-5-cyclopropyl-4H-pyrrolo[3,4-d]thiazol-6(5H)-one (CAS 1446716-55-7)
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- 4-Aminocinnoline (CAS 5152-83-0)
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