6-Acetyl-8-fluoro-3,4-dihydroquinolin-2(1H)-one CAS 143268-80-8

Purity 97%+In StockPharmaceutical Standards
CAS No.143268-80-8
Molecular FormulaC11H10FNO2
Molecular Weight207.20 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-Acetyl-8-fluoro-3,4-dihydroquinolin-2(1H)-one CAS 143268-80-8 chemical structure

Description

The occurrence of 6-Acetyl-8-fluoro-3,4-dihydroquinolin-2(1H)-one is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

6-Acetyl-8-fluoro-3,4-dihydroquinolin-2(1H)-one (CAS 143268-80-8) is a high-purity analytical reference standard with the molecular formula C11H10FNO2 and a molecular weight of 207.20 g/mol.

Structurally, 6-Acetyl-8-fluoro-3,4-dihydroquinolin-2(1H)-one (C11H10FNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 207.20 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 6-Acetyl-8-fluoro-3,4-dihydroquinolin-2(1H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC11H10FNO2
Molecular Weight207.20 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1997
Halogen ContentF-containing
Nitrogen Atoms1

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