[3-bromo-2-(difluoromethoxy)phenyl]methanamine hydrochloride CAS 1432681-22-5
| CAS No. | 1432681-22-5 |
| Molecular Formula | C8H8BrF2NO |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
[3-bromo-2-(difluoromethoxy)phenyl]methanamine hydrochloride (CAS 1432681-22-5), molecular formula C8H8BrF2NOHCl and molecular weight 288.52 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of [3-bromo-2-(difluoromethoxy)phenyl]methanamine hydrochloride (C8H8BrF2NOHCl) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H8BrF2NO HCl |
| Molecular Weight | 288.52 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related bromo Standards
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- 14-Bromo-1-tetradecyne (CAS 1000014-24-3)
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Recommended Standards
- (4S,5S,6S,7R)-5,7-Dimethoxy-4,6-dimethyl-8-(phenylmethoxy)-1-octanol (CAS 276690-17-6)
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- 5,5-Difluoroazepan-4-one hydrochloride (CAS 2097991-20-1)
- N-(4-chlorophenyl)-2-(2,3,5,6-tetrafluoro-4-methylphenyl)hydrazine-1-carbothioamide (CAS 946387-19-5)
- (3-Pentafluoroethyloxy-propyl)-(3-trifluoromethyl-benzyl)-amine (CAS 1208079-21-3)
- [4-(3-Quinolinyl)phenyl]acetonitrile (CAS 112177-31-8)
- Ethyl 6-nitro-2-(trifluoromethyl)imidazo[1,2-a]pyridine-3-carboxylate (CAS 2407339-51-7)
- 2-(2,6-Dichlorophenyl)-1H-imidazo[4,5-c]pyridin-4-ol (CAS 1334411-80-1)
- R-Thalidomide (CAS 2614-06-4)
- D-[Ser]11-Semaglutide (CAS CATO-CPTD788629)
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