4-Bromo-2-isonicotinoylthiophene-3-carboxylic acid CAS 1433203-86-1
| CAS No. | 1433203-86-1 |
| Molecular Formula | C11H6BrNO3S |
| Molecular Weight | 312.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-Bromo-2-isonicotinoylthiophene-3-carboxylic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-Bromo-2-isonicotinoylthiophene-3-carboxylic acid (CAS 1433203-86-1) is a high-purity analytical reference standard with the molecular formula C11H6BrNO3S and a molecular weight of 312.14 g/mol.
The molecular framework of 4-Bromo-2-isonicotinoylthiophene-3-carboxylic acid (C11H6BrNO3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-Bromo-2-isonicotinoylthiophene-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H6BrNO3S |
| Molecular Weight | 312.14 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Bromo Standards
- 4-Bromo-N-(1-ethyl-1h-pyrazol-4-yl)-2-fluorobenzamide (CAS 1154950-11-4)
- 2-Bromo-N-(1-ethyl-1h-pyrazol-4-yl)-5-fluorobenzamide (CAS 1154950-19-2)
- 2-Bromo-N-(1-ethyl-1h-pyrazol-4-yl)-4-fluorobenzamide (CAS 1154950-40-9)
- 2-Bromo-5-(4-nitrobenzoyl)thiophene (CAS 909421-68-7)
- 4-Bromo-2-fluoro-N-(2-(furan-2-yl)ethyl)benzamide (CAS 1010228-68-8)
- 5-Bromo-N-(3-fluoro-4-methylbenzyl)furan-2-carboxamide (CAS 1043267-09-9)
- (4-Bromo-benzyl)-(1-methyl-2-trifluoromethoxyethyl)-amine (CAS 1208078-75-4)
- 4-(4-Bromo-2-difluoromethoxyphenyl)-thiosemicarbazide (CAS 1303993-91-0)
Recommended Standards
- 4,4,5,5-Tetramethyl-2-(4-(1-(trifluoromethyl)cyclopropyl)phenyl)-1,3,2-dioxaborolane (CAS 1431983-70-8)
- (E)-4,4,5,5-Tetramethyl-2-(3-(4-(trifluoromethyl)phenyl)prop-1-en-1-yl)-1,3,2-dioxaborolane (CAS 1444827-08-0)
- 4,4,5,5-Tetramethyl-2-((1R,2R)-2-(4-(trifluoromethyl)phenyl)cyclopropyl)-1,3,2-dioxaborolane (CAS 1240492-30-1)
- (E)-4,4,5,5-Tetramethyl-2-(2-(4-(trifluoromethyl)phenyl)prop-1-en-1-yl)-1,3,2-dioxaborolane (CAS 2021203-43-8)
- 4-(Benzyloxy)-4'-methylbiphenyl (CAS 449737-22-8)
- 2-(1-Benzyl-5-methylpyrrolidin-3-yl)ethan-1-amine (CAS 1423029-37-1)
- Spiro[5.5]undecane-2-carboxylic acid (CAS 1147732-99-7)
- (R)-2-Amino-3-(2-aminophenyl)propanoic acid (CAS 35987-77-0)
- n-Ethyl-2-(ethylamino)acetamide (CAS 97454-46-1)
- 3-(4-Methoxybenzyl)-1,3,7-triazaspiro[4.4]nonane-2,4-dione hydrochloride (CAS 1956365-90-4)
- 4-Bromo-2-chloro-1-(vinyloxy)benzene (CAS 869569-67-5)
- Terbinafine (CAS 91161-71-6)
- 6α-Fluprednisolone (CAS 53-34-9)
- [D-Ser8]-Semaglutide A (CAS CATO-C4X-2226116)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com