(R)-5-Bromo-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole CAS 143322-57-0

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (R)-5-Bromo-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole.

(R)-5-Bromo-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole (CAS 143322-57-0), molecular formula C14H17BrN2 and molecular weight 293.20 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of (R)-5-Bromo-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole (C14H17BrN2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (R)-5-Bromo-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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