8-Chloro-6-methylimidazo[1,2-a]pyrazine CAS 143591-86-0
| CAS No. | 143591-86-0 |
| Molecular Formula | C7H6ClN3 |
| Molecular Weight | 167.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 8-Chloro-6-methylimidazo[1,2-a]pyrazine.
8-Chloro-6-methylimidazo[1,2-a]pyrazine (CAS 143591-86-0), molecular formula C7H6ClN3 and molecular weight 167.60 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 8-Chloro-6-methylimidazo[1,2-a]pyrazine (C7H6ClN3) contains a nitrile group, chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 167.60 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 8-Chloro-6-methylimidazo[1,2-a]pyrazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H6ClN3 |
| Molecular Weight | 167.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 4-Chloro-1H-pyrrolo[2,3-b]pyridin-3-amine (CAS 1000340-38-4)
- 6-Chloro-1H-pyrrolo[2,3-b]pyridin-4-amine (CAS 1000340-80-6)
- 5-Chloro-1H-pyrrolo[3,2-b]pyridin-7-amine (CAS 1000577-90-1)
- 5-Chloro-1H-indazol-6-amine (CAS 100960-35-8)
- 3-chloro-6-methyl-[1,2,4]triazolo[4,3-a]pyridine (CAS 1020036-37-6)
- 7-Chloro-1H-benzo[d]imidazol-5-amine (CAS 10597-54-3)
- 6-Chloro-1H-benzo[d]imidazol-4-amine (CAS 10597-55-4)
- 2-Chloro-7-methyl-7H-pyrrolo[2,3-d]pyrimidine (CAS 1060816-67-2)
Recommended Standards
- 7-Chloro-1H-pyrrolo[2,3-c]pyridin-4-amine (CAS 1427502-60-0)
- 1-(4-Chloro-1H-pyrazol-1-yl)cyclopropane-1-carbonitrile (CAS 1469286-91-6)
- 5-Chloro-2-(methylimino)-1,2-dihydropyridine-3-carbonitrile (CAS 1427460-56-7)
- 6-Chloro-2-methylimidazo[1,2-b]pyridazine (CAS 14793-00-1)
- 3-(4-Ethoxycarbonylphenyl)isonicotinic acid (CAS 1261929-79-6)
- (3-(Morpholinosulfonyl)benzoyl)-L-valine (CAS 956261-04-4)
- Ethyl 4-amino-5-fluoronicotinate (CAS 1805741-10-9)
- 4-amino-N-(3-amino-3-oxopropyl)benzamide (CAS 1114822-89-7)
- 1-Butyl-N-phenyl-1H-benzo[d]imidazol-2-amine (CAS 630091-65-5)
- tert-butyl N-(6-methylenespiro[2.5]octan-2-yl)carbamate (CAS 2294127-96-9)
- N6-(((9H-fluoren-9-yl)methoxy)carbonyl)-N2-(tert-butoxycarbonyl)-N2-methyl-L-lysine (CAS 1799443-43-8)
- 2,6-Di-Tert-Butyl-4-Methoxyphenol (CAS 489-01-0)
- Quinoline, 6-dodecyl-1,2-dihydro-2,2,4-trimethyl- (CAS 89-28-1)
- Liraglutide-d8 Tritrifluoroacetate (CAS CATO-C4X-199223)
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