(R)-2,2',3,3'-Tetrahydro-6,6'-bis[4-(trifluoromethyl)phenyl]-1,1'-spirobi[1H-indene]-7,7'-diol CAS 1435948-34-7
| CAS No. | 1435948-34-7 |
| Molecular Formula | C31H22F6O2 |
| Molecular Weight | 540.50 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (R)-2,2',3,3'-Tetrahydro-6,6'-bis[4-(trifluoromethyl)phenyl]-1,1'-spirobi[1H-indene]-7,7'-diol is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(R)-2,2',3,3'-Tetrahydro-6,6'-bis[4-(trifluoromethyl)phenyl]-1,1'-spirobi[1H-indene]-7,7'-diol (CAS 1435948-34-7), molecular formula C31H22F6O2 and molecular weight 540.50 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C31H22F6O2, (R)-2,2',3,3'-Tetrahydro-6,6'-bis[4-(trifluoromethyl)phenyl]-1,1'-spirobi[1H-indene]-7,7'-diol contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 540.50 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C31H22F6O2 |
| Molecular Weight | 540.50 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
Related R Standards
- (S)-2,2',3,3'-Tetrahydro-6,6'-bis[4-(trifluoromethyl)phenyl]-1,1'-spirobi[1H-indene]-7,7'-diol (CAS 1621066-71-4)
- Tetrahydro-11-deoxy Cortisol 21-O-beta-D-Glucuronide (CAS 56162-38-0)
- Tetrahydro-11-deoxy Cortisol 3-O-beta-D-Glucuronide (CAS 56162-40-4)
- (11aS)-10,11,12,13-Tetrahydro-5-hydroxy-3,7-bis(4-nitrophenyl)-diindeno[7,1-de:1',7'-fg][1,3,2]dioxaphosphocin-5-oxide (CAS 1412439-84-9)
- 11-∆9-Tetrahydro Cannabinol-9-carboxylic Acid β-D-Glucuronide (CAS 84376-63-6)
- 11-Nor-∆9-Tetrahydro Cannabinol-9-carboxylate Acyl-β-D-glucuronide (CAS 76448-35-6)
- (R)-2,2',3,3'-Tetrahydro-1,1'-spirobi[indene]-7,7'-diyl bis(trifluoromethanesulfonate) (CAS 528521-72-4)
- (11aS)-10,11,12,13-Tetrahydro-N,N-bis[(1S)-1-(2-methoxyphenyl)ethyl]diindeno[7,1-de:1′,7′-fg][1,3,2]dioxaphosphocin-5-amine (CAS 1642865-92-6)
Recommended Standards
- Azilsartan Impurity 33 (CAS 1417576-00-1)
- Azilsartan Impurity 162 (CAS CATO-C4X-1096162)
- 2-((3-(4-Bromophenyl)-4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)-N-(o-tolyl)acetamide (CAS 476484-30-7)
- methyl (2S)-4-(3-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4,6-dimethyl-9-oxo-4,9-dihydro-3H-imidazo[1,2-a]purin-7-yl)-3-hydroperoxy-2-((methoxycarbonyl)amino)butanoate (CAS 78355-49-4)
- Ethyl 3-amino-8-azabicyclo[3.2.1]Octane-8-carboxylate (CAS 638193-50-7)
- Tert-butyl 4-hydroxy-3,4-dihydropyridine-1(2H)-carboxylate (CAS 643759-64-2)
- 3-(1H-Indazol-3-yl)propanoic acid (CAS 214541-51-2)
- 5,5-Dimethyl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole-3-carboxylic acid (CAS 2411244-72-7)
- 8-Bromo-7-(2-chloroethyl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione (CAS 115415-41-3)
- m-PEG24-NHS ester (CAS 2395839-96-8)
- GST-HG171 Impurity 8 (CAS CATO-C4X-30608)
- (3R,4S)-4-(4-methoxyphenyl)-2-oxopyrrolidine-3-carboxylic acid (CAS 1784747-95-0)
- 4-(2-Benzyl-4-chlorophenoxy)piperidine (CAS 946681-57-8)
- Semaglutide Impurity 185 (CAS CATO-C4X-2226185)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com