4-Chloro-5-(4-nitrophenyl)nicotinonitrile CAS 1436405-49-0
| CAS No. | 1436405-49-0 |
| Molecular Formula | C12H6ClN3O2 |
| Molecular Weight | 259.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 259.65 g/mol gives 4-Chloro-5-(4-nitrophenyl)nicotinonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 4-Chloro-5-(4-nitrophenyl)nicotinonitrile (CAS 1436405-49-0), a certified reference material (molecular formula C12H6ClN3O2, MW 259.65 g/mol) for analytical method development and quality control.
4-Chloro-5-(4-nitrophenyl)nicotinonitrile (C12H6ClN3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Chloro-5-(4-nitrophenyl)nicotinonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H6ClN3O2 |
| Molecular Weight | 259.65 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- N-(2-((2-Chloro-5-nitropyrimidin-4-yl)amino)ethyl)acetamide (CAS 1068607-13-5)
- ethyl 4-chloro-6-(trifluoromethyl)pyridine-3-carboxylate (CAS 1196146-35-6)
- 1-(4-Chloro-3-(trifluoromethyl)phenyl)cyclobutane-1-carbonitrile (CAS 1314655-92-9)
- 1-[3-Chloro-5-(trifluoromethyl)phenyl]cyclobutanecarbonitrile (CAS 1314772-15-0)
- 4-Chloro-2,3-dimethyl-7-(trifluoromethyl)quinoline (CAS 1707377-48-7)
- 4-Chloro-2,3-dimethyl-6-(trifluoromethyl)quinoline (CAS 1713463-07-0)
- 2-Chloro-6-morpholino-5-nitropyrimidin-4-amine (CAS 29955-44-0)
- Ethyl (6-Chloro-2-nitro-3-pyridyl)(methyl)carbamate (CAS 89660-17-3)
Recommended Standards
- Dimethyl (4-chloropyridine-2,6-diyl)dicarbamate (CAS 121572-37-0)
- 2-Amino-8-chloro-9-((2-hydroxyethoxy)methyl)-1H-purin-6(9H)-one (CAS 91897-98-2)
- Solifenacin Impurity 25 (CAS 46834-56-4)
- Ethyl 6-chloro-4-(methylamino)-5-nitropyridine-3-carboxylate (CAS 925427-22-1)
- Chlorpropamide (CAS 94-20-2)
- 1,4-Diamino-7-chloro-2-(4-methoxyphenoxy)anthracene-9,10-dione (CAS 88605-34-9)
- 1-(2-Chloro-1-ethoxyethyl)-1H-benzo[d][1,2,3]triazole (CAS 23269-82-1)
- (3,3,3-Trifluoroprop-1-en-1-yl)boronic acid (CAS 2070921-72-9)
- 4-[(1Z)-[(4H-1,2,4-Triazol-4-yl)imino]methyl]benzonitrile (CAS 35546-42-0)
- methyl (3R,4S)-4-(tert-butoxycarbonylamino)-3-hydroxy-cyclopentene-1-carboxylate (CAS 329910-37-4)
- 2-bromopyrazolo[5,1-b]thiazole-7-carboxylic acid (CAS 2796324-14-4)
- 2-Propenoic acid, 2-methyl-, butyl ester, polymer with 2-(3-oxazolidinyl)ethyl 2-methyl-2-propenoate (CAS 39935-66-5)
- 2-[(benzylamino)methyl]-3,4-dihydroquinazolin-4-one (CAS 143993-14-0)
- Insulin Degludec Impurity 18 (CAS CATO-C4X-215718)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com