2-(6-Fluoro-4-methylquinolin-2-yl)acetonitrile CAS 1437385-57-3
| CAS No. | 1437385-57-3 |
| Molecular Formula | C12H9FN2 |
| Molecular Weight | 200.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(6-Fluoro-4-methylquinolin-2-yl)acetonitrile (CAS 1437385-57-3), molecular formula C12H9FN2 and molecular weight 200.21 g/mol, is a CATO reference standard with documented purity and traceability.
2-(6-Fluoro-4-methylquinolin-2-yl)acetonitrile (C12H9FN2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(6-Fluoro-4-methylquinolin-2-yl)acetonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H9FN2 |
| Molecular Weight | 200.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluoro Standards
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- 3-Fluoro-2-(2-methoxyethoxy)anisole (CAS 1352318-45-6)
- 2-Fluoro-3-phenylbenzaldehyde (CAS 1508348-13-7)
- (5-Fluoro-3,4-dimethoxy-2-methylphenyl)methanol (CAS 1809337-14-1)
- 2-Fluoro-4-phenylbenzaldehyde (CAS 183436-80-8)
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- 4'-Fluoro-[1,1'-biphenyl]-2-carbaldehyde (CAS 192863-46-0)
- 1-(4-Fluoro-1H-indol-3-yl)cyclopropane-1-carbonitrile (CAS 2110917-08-1)
Recommended Standards
- Dimethyl thiophene-2,3-dicarboxylate (CAS 14300-68-6)
- 2-(difluoromethyl)-1,3-benzothiazol-6-amine (CAS 1468986-20-0)
- 2-(5-(Methoxycarbonyl)thiophen-2-yl)acetic acid (CAS 142667-06-9)
- (5,7-Difluorobenzo[b]thiophen-2-yl)methanol (CAS 1400702-19-3)
- (5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methanol (CAS 1934391-22-6)
- 3,4-Diaminobenzoic Acid (CAS 619-05-6)
- (5-Carbamoylpyridin-2-yl)boronic acid (CAS 1164100-83-7)
- (2-Hydroxy-3-iodophenyl)boronic acid (CAS 1245635-13-5)
- 2-(3-Ethynylphenyl)ethan-1-amine (CAS 949115-77-9)
- N-Methoxy-N-methyl-1H-pyrazole-5-carboxamide (CAS 162468-84-0)
- 2-(Benzylthio)-3-phenylthieno[3,2-d]pyrimidin-4(3H)-one (CAS 338417-81-5)
- 3-(Trifluoromethyl)benzoic anhydride (CAS 25753-15-5)
- 6-Nitroquinoline-2-carboxamide (CAS 1267474-65-6)
- Semaglutide impurity 44 (CAS CATO-C4X-222644)
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