Des-(1-(sec-butyl)-1H-1,2,4-triazol-5(4H)-one) Itraconazole CAS 1437468-62-6

Purity 97%+In StockPharmaceutical Standards
CAS No.1437468-62-6
Molecular FormulaC29H30Cl2N6O3
Molecular Weight581.49 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Des-(1-(sec-butyl)-1H-1,2,4-triazol-5(4H)-one) Itraconazole CAS 1437468-62-6 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Des-(1-(sec-butyl)-1H-1,2,4-triazol-5(4H)-one) Itraconazole.

CATO supplies Des-(1-(sec-butyl)-1H-1,2,4-triazol-5(4H)-one) Itraconazole (CAS 1437468-62-6), a certified reference material (molecular formula C29H30Cl2N6O3, MW 581.49 g/mol) for analytical method development and quality control.

Des-(1-(sec-butyl)-1H-1,2,4-triazol-5(4H)-one) Itraconazole (C29H30Cl2N6O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures Des-(1-(sec-butyl)-1H-1,2,4-triazol-5(4H)-one) Itraconazole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC29H30Cl2N6O3
Molecular Weight581.49 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)17.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Halogen ContentCl-containing
Nitrogen Atoms6

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