3-(6-Phenylthiazolo[3,2-b][1,2,4]triazol-2-yl)propanoic acid CAS 1437482-65-9
| CAS No. | 1437482-65-9 |
| Molecular Formula | C13H11N3O2S |
| Molecular Weight | 273.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-(6-Phenylthiazolo[3,2-b][1,2,4]triazol-2-yl)propanoic acid (C13H11N3O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
3-(6-Phenylthiazolo[3,2-b][1,2,4]triazol-2-yl)propanoic acid (CAS 1437482-65-9) is a high-purity analytical reference standard with the molecular formula C13H11N3O2S and a molecular weight of 273.31 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(6-Phenylthiazolo[3,2-b][1,2,4]triazol-2-yl)propanoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H11N3O2S |
| Molecular Weight | 273.31 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Phenylthiazolo Standards
- 3-(5-Methyl-6-phenylthiazolo[3,2-b][1,2,4]triazol-2-yl)propanoic acid (CAS 1437385-40-4)
- Ethyl 2-(2-phenylthiazolo[3,2-b][1,2,4]triazol-6-yl)acetate (CAS 66870-63-1)
- 2-(6-Phenylthiazolo[3,2-b][1,2,4]triazol-5-yl)acetic acid (CAS 1437457-75-4)
- 2-((2-Methyl-7-phenylthiazolo[4,5-d]pyridazin-4-yl)thio)acetonitrile (CAS 946228-54-2)
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- 3-Phenylthiazolo[5,4-d]isoxazol-5-amine (CAS 193345-25-4)
- 6-Methyl-5-phenylthiazolo[3,2-b][1,2,4]triazole (CAS 1423121-02-1)
- 2-Phenylthiazolo[5,4-c]pyridine (CAS 52334-38-0)
Recommended Standards
- 2-(6-(P-tolyl)thiazolo[3,2-b][1,2,4]triazol-5-yl)acetic acid (CAS 1437480-95-9)
- (2E)-3-(5-Methylthiophen-2-yl)-1-(3-nitrophenyl)prop-2-en-1-one (CAS 1440663-62-6)
- 3-(2-Hydroxy-2-methylbenzo[d]oxazol-3(2H)-yl)propane-1-sulfonic acid (CAS 143413-71-2)
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