Enzalutamide Impurity N7 CAS 143782-23-4
| CAS No. | 143782-23-4 |
| Molecular Formula | C9H3F3N2S |
| Molecular Weight | 228.19 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Enzalutamide Impurity N7 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Enzalutamide Impurity N7 (CAS 143782-23-4, C9H3F3N2S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Enzalutamide Impurity N7 (C9H3F3N2S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C9H3F3N2S |
| Molecular Weight | 228.19 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Enzalutamide Standards
- Enzalutamide Impurity 39 (CAS CATO-C4X-101639)
- Enzalutamide Impurity 40 (CAS 3079438-61-9)
- Enzalutamide Impurity 63 (CAS 2997797-11-0)
- Enzalutamide Impurity 5 (CAS 179232-29-2)
- Enzalutamide Impurity 64 (CAS CATO-C4X-101664)
- Enzalutamide Impurity 68 (CAS CATO-C4X-101668)
- Enzalutamide Impurity 30 (CAS 112704-79-7)
- Enzalutamide Impurity 6 (CAS 1332524-02-3)
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