4-((tert-Butyldimethylsilyl)oxy)-1-phenylbutan-1-one CAS 143878-47-1

Purity 97%+In StockPharmaceutical Standards
CAS No.143878-47-1
Molecular FormulaC16H26O2Si
Molecular Weight278.46 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-((tert-Butyldimethylsilyl)oxy)-1-phenylbutan-1-one CAS 143878-47-1 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO supplies 4-((tert-Butyldimethylsilyl)oxy)-1-phenylbutan-1-one (CAS 143878-47-1), a certified reference material (molecular formula C16H26O2Si, MW 278.46 g/mol) for analytical method development and quality control.

Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system, 4-((tert-Butyldimethylsilyl)oxy)-1-phenylbutan-1-one is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 278.46 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

As a certified reference material (CRM), 4-((tert-Butyldimethylsilyl)oxy)-1-phenylbutan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC16H26O2Si
Molecular Weight278.46 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity97%+
StorageStore at room temperature
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1998

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