4-Chloro-5-iodoquinoline CAS 143946-46-7
| CAS No. | 143946-46-7 |
| Molecular Formula | C9H5ClIN |
| Molecular Weight | 289.50 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 289.50 g/mol gives 4-Chloro-5-iodoquinoline distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-Chloro-5-iodoquinoline (CAS 143946-46-7) is a high-purity analytical reference standard with the molecular formula C9H5ClIN and a molecular weight of 289.50 g/mol.
4-Chloro-5-iodoquinoline (C9H5ClIN) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/iodine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H5ClIN |
| Molecular Weight | 289.50 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Cl/I-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 8-Chloro-6-iodoquinoline (CAS 111454-67-2)
- 1-Chloro-7-iodoisoquinoline (CAS 1170704-54-7)
- 7-Chloro-1-iodoisoquinoline (CAS 1203579-27-4)
- 6-chloro-4-iodopyridine-3-carboxylic acid (CAS 1211578-80-1)
- 2-Chloro-6-iodoquinoline (CAS 124467-20-5)
- 2-Chloro-3-iodoquinoline (CAS 128676-85-7)
- 2-Chloro-8-iodoquinoline (CAS 1339174-14-9)
- 1-Chloro-5-iodoisoquinoline (CAS 1379322-93-6)
Recommended Standards
- 7-Chloro-3-iodoquinoline (CAS 1424245-91-9)
- 3-Chloro-5-iodo-isoquinoline (CAS 1695831-18-5)
- 6-Chloro-3-iodoquinoline (CAS 1416801-72-3)
- 3-Chloro-7-iodoisoquinoline (CAS 1841079-91-1)
- 5-Fluoro-2-(piperidin-4-ylmethoxy)pyrimidine hydrochloride (CAS 1353965-96-4)
- Benzyl 3-((2-aminoethyl)(ethyl)amino)pyrrolidine-1-carboxylate (CAS 1353976-24-5)
- 5-Tert-butyl-1,2,4-oxadiazol-3-amine (CAS 91362-43-5)
- Ethyl 10-oxooctadecanoate (CAS 18490-59-0)
- Fenchlorphos (CAS 299-84-3)
- 2-(((4-Chlorophenyl)amino)methyl)-6-methoxyphenol (CAS 196617-60-4)
- N,3-Dimethyl-2-nitroaniline (CAS 70254-75-0)
- 7-Chloro-4-(1-methylhydrazinyl)quinoline (CAS 51708-15-7)
- di-tert-Butyl 2-methylenemalonate (CAS 86633-09-2)
- D-Gln24-Tirzepatide (CAS CATO-CPTD788910)
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