Febuxostat Impurity 48 CAS 144060-52-6
| CAS No. | 144060-52-6 |
| Molecular Formula | C15H14N2O3S |
| Molecular Weight | 302.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Febuxostat Impurity 48 (C15H14N2O3S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Febuxostat Impurity 48 (CAS 144060-52-6) is a certified pharmaceutical impurity reference standard with the molecular formula C15H14N2O3S and a molecular weight of 302.35 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Febuxostat Impurity 48 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H14N2O3S |
| Molecular Weight | 302.35 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Febuxostat Standards
- Febuxostat Impurity 25 (CAS 1530308-87-2)
- Febuxostat Impurity 87 (CAS CATO-C4X-116287)
- Febuxostat Impurity 1 (CAS CATO-C4X-11621)
- Febuxostat Impurity 111 (CAS CATO-C4X-1162111)
- Febuxostat Impurity 97 (CAS CATO-C4X-116297)
- Febuxostat Impurity 49 (CAS 1206550-99-3)
- Febuxostat Impurity 56 (CAS CATO-C4X-116256)
- Febuxostat impurity 129 (CAS CATO-C4X-1162105)
Recommended Standards
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- 2-Hydroxy-5-(trifluoromethyl)phenylboronic acid (CAS 779329-55-4)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com