ethyl 2,2-difluoro-2-(6-fluoro-2-methyl-2H-indazol-5-yl)acetate CAS 1440965-40-1
| CAS No. | 1440965-40-1 |
| Molecular Formula | C12H19F3N2O2 |
| Molecular Weight | 280.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including ethyl 2,2-difluoro-2-(6-fluoro-2-methyl-2H-indazol-5-yl)acetate.
CATO supplies ethyl 2,2-difluoro-2-(6-fluoro-2-methyl-2H-indazol-5-yl)acetate (CAS 1440965-40-1), a certified reference material (molecular formula C12H19F3N2O2, MW 280.29 g/mol) for analytical method development and quality control.
Based on its molecular formula C12H19F3N2O2, ethyl 2,2-difluoro-2-(6-fluoro-2-methyl-2H-indazol-5-yl)acetate contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 280.29 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H19F3N2O2 |
| Molecular Weight | 280.29 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
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- 6-Bromo-5-nitro-2,3-dihydro-1h-inden-1-one (CAS 158205-20-0)
- 2-Fluoro-4-[7-(2-methyl-4-pyridinyl)imidazo[1,2-a]pyridin-3-yl]-N-[3-(trifluoromethyl)phenyl]-Benzeneacetamide (CAS 908265-94-1)
- 2-(4-Bromothiophen-2-yl)-2-morpholinoacetic acid (CAS 1247749-20-7)
- 2-Chloro-1-ethoxy-4-methoxybenzene (CAS 1881296-39-4)
- Isoxazol-4-yl(isoxazol-5-yl)methanone (CAS 844681-18-1)
- (E)-2-(4-((4-fluorobenzyl)oxy)-3-methoxyphenyl)-N-(3-methoxybenzyl)ethene-1-sulfonamide (CAS 339104-63-1)
- 6-Bromoisoquinolin-4-ol (CAS 1015070-56-0)
- 2-Chloro-N-(2-(dimethylamino)ethyl)acetamide (CAS 788779-09-9)
- Semaglutide impurity 208 (CAS CATO-C4X-2226208)
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