2-Bromo-4-chloro-5-methoxypyrimidine CAS 1441422-32-7
| CAS No. | 1441422-32-7 |
| Molecular Formula | C5H4BrClN2O |
| Molecular Weight | 223.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Bromo-4-chloro-5-methoxypyrimidine (C5H4BrClN2O) contains an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
2-Bromo-4-chloro-5-methoxypyrimidine (CAS 1441422-32-7), molecular formula C5H4BrClN2O and molecular weight 223.46 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Bromo-4-chloro-5-methoxypyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H4BrClN2O |
| Molecular Weight | 223.46 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 4-Bromo-1-methyl-1H-pyrazole-5-carbonyl chloride (CAS 1006448-72-1)
- 5-Bromo-2-chloro-4-hydrazinylpyrimidine (CAS 1021268-16-5)
- 5-Bromo-6-chloro-2-methyl-1H-pyrimidin-4-one (CAS 105806-11-9)
- 5-Bromo-4-chloro-2-methylpyridazin-3(2H)-one (CAS 1123-58-6)
- 5-Bromo-6-chloro-3-methylpyrimidin-4(3H)-one (CAS 117113-95-8)
- 4-Bromo-6-chloro-2-methylpyridazin-3(2H)-one (CAS 1178884-53-1)
- 1-(3-Bromo-5-chloropyrazin-2-yl)hydrazine (CAS 1374652-24-0)
- 4-Bromo-2-chloro-5-methoxypyrimidine (CAS 1441422-23-6)
Recommended Standards
- 4-Bromo-6-chloro-3-methoxypyridazine (CAS 1445774-08-2)
- 4-Bromo-5-methyl-1H-pyrazole-3-carbonyl chloride (CAS 1858240-13-7)
- 2-Bromo-5-chloro-3-methoxypyrazine (CAS 1934706-52-1)
- (5-Bromo-3-chloropyrazin-2-yl)hydrazine (CAS 850421-08-8)
- Tebufloquin (CAS 376645-78-2)
- 4-Chloro-2-fluoro-3-(4-methylpiperazinomethyl) benzophenone (CAS 898789-18-9)
- Ethyl (3S,5S)-5-(tert-butyl)thiomorpholine-3-carboxylate (CAS 1452829-48-9)
- 2,5-Fifluoro-4-formylbenzoic acid (CAS 1890953-67-9)
- 2-Amino-1-(4,5,6,7-tetrahydro-1-benzothiophen-2-yl)ethan-1-one hydrochloride (CAS 263148-70-5)
- 2-Chloro-4,5,6-trimethylpyridine-3-carboxylic acid (CAS 1500393-24-7)
- (R)-2-((tert-Butoxycarbonyl)amino)-3-((cyanomethyl)thio)propanoic acid (CAS 174894-18-9)
- 3-(5-Iodo-3-(trifluoromethyl)-1H-pyrazol-1-yl)pyridine (CAS 1255041-96-3)
- 6-Methyl-5,6-dihydroindolizine (CAS 355114-79-3)
- Neuropeptide Y, human (CAS 98264-90-5)
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