5-(3-Fluorophenyl)-4-methyl-2,4-dihydro-3H-1,2,4-triazole-3-thione CAS 144165-22-0

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(3-Fluorophenyl)-4-methyl-2,4-dihydro-3H-1,2,4-triazole-3-thione.

CATO supplies 5-(3-Fluorophenyl)-4-methyl-2,4-dihydro-3H-1,2,4-triazole-3-thione (CAS 144165-22-0), a certified reference material (molecular formula C9H8FN3S, MW 209.24 g/mol) for analytical method development and quality control.

5-(3-Fluorophenyl)-4-methyl-2,4-dihydro-3H-1,2,4-triazole-3-thione (C9H8FN3S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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