4,5-Dichloro-2-(4-methoxybenzyl)pyridazin-3(2H)-one CAS 144172-54-3
| CAS No. | 144172-54-3 |
| Molecular Formula | C12H10Cl2N2O2 |
| Molecular Weight | 285.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 4,5-Dichloro-2-(4-methoxybenzyl)pyridazin-3(2H)-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 285.13 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
4,5-Dichloro-2-(4-methoxybenzyl)pyridazin-3(2H)-one (CAS 144172-54-3), molecular formula C12H10Cl2N2O2 and molecular weight 285.13 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4,5-Dichloro-2-(4-methoxybenzyl)pyridazin-3(2H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H10Cl2N2O2 |
| Molecular Weight | 285.13 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Dichloro Standards
- 2-(4,5-Dichloro-1H-imidazol-1-yl)-1-(4-methoxyphenyl)ethan-1-one (CAS 1219582-14-5)
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- 3,5-Dichloro-1-[(4-methoxyphenyl)-methyl]-1,2-dihydropyrazin-2-one (CAS 393860-82-7)
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Recommended Standards
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- Methyl (1s,3s)-1-(4-bromophenyl)-3-hydroxycyclobutane-1-carboxylate (CAS 1402603-94-4)
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- tert-Butyl (4-(2-oxoethyl)phenyl)carbamate (CAS 695171-91-6)
- 2-Cyano-3-Ethoxy-Acrylic Acid Ethyl Ester (CAS 94-05-3)
- tert-Butyl 3-phenyl-1,2,3,4-tetrahydroquinoxaline-1-carboxylate (CAS 912763-02-1)
- (2R,3R,4R)-5-(benzyloxy)-2,3,4-trihydroxypentanal (CAS 72369-89-2)
- 1,2-Diphenyl-1,5,6,7-tetrahydro-4H-indol-4-one (CAS 14073-27-9)
- 5-Bromo-2-(4-fluorophenyl)-6-(methylsulfonamido)benzofuran-3-carboxylic acid (CAS 1333244-32-8)
- (1S,3aR,6aS)-2-((S)-2-((R)-2-cyclohexyl-2-(pyrazine-2-carboxamido)acetamido)-3,3-dimethylbutanoyl)octahydrocyclopenta[c]pyrrole-1-carboxylic acid (CAS 1616728-85-8)
- 4-(Pyridin-2-ylsulfonyl)morpholine (CAS 106762-44-1)
- Semaglutide impurity 51 (CAS CATO-C4X-222651)
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