2-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)propan-2-ol hydrochloride CAS 1441765-57-6
| CAS No. | 1441765-57-6 |
| Molecular Formula | C14H22BNO3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
2-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)propan-2-ol hydrochloride (CAS 1441765-57-6) is a high-purity analytical reference standard with the molecular formula C14H22BNO3HCl and a molecular weight of 299.60 g/mol.
2-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)propan-2-ol hydrochloride (C14H22BNO3HCl) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C14H22BNO3 HCl |
| Molecular Weight | 299.60 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Tetramethyl Standards
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Recommended Standards
- (R)-5,6,7,8-Tetrahydro-isoquinolin-8-ylamine dihydrochloride (CAS 1965305-44-5)
- ethyl 4-bromo-6-fluoro-quinoline-3-carboxylate (CAS 1242260-48-5)
- tert-Butyl (S)-2-(2-chlorophenyl)piperazine-1-carboxylate (CAS 1240590-55-9)
- LY-3130481, >98% (HPLC) (CAS 1610802-47-5)
- 5-Amino-4-fluoro-N-isobutyl-2-methylbenzamide (CAS 1876008-72-8)
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- 4-Cyclopropoxy-3-(trifluoromethyl)benzenesulfonamide (CAS 1243454-02-5)
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- 3-Chloro-4-(cyclopentyloxy)-5-methoxybenzoic acid (CAS 693812-85-0)
- Mast Cell Degranulating (MCD) Peptide HR-2 (CAS 80388-04-1)
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