Nalmefene Impurity 10 CAS 144265-45-2
| CAS No. | 144265-45-2 |
| Molecular Formula | C22H27NO3 |
| Molecular Weight | 353.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 353.45 g/mol gives Nalmefene Impurity 10 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Nalmefene Impurity 10 (CAS 144265-45-2) is a certified pharmaceutical impurity reference standard with the molecular formula C22H27NO3 and a molecular weight of 353.45 g/mol.
Structurally, Nalmefene Impurity 10 (C22H27NO3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 353.45 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Nalmefene Impurity 10 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H27NO3 |
| Molecular Weight | 353.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 1 |
Related Nalmefene Standards
- Nalmefene Impurity 14 (CAS CATO-C4X-126814)
- Nalmefene Impurity 26 (CAS CATO-C4X-126826)
- Nalmefene Impurity 15 (CAS CATO-C4X-126815)
- Nalmefene Impurity 16 (CAS CATO-C4X-126816)
- Nalmefene Impurity 17 (CAS CATO-C4X-126817)
- Nalmefene Impurity 25 (CAS CATO-C4X-126825)
- Nalmefene Impurity 7 (CAS CATO-C4X-12687)
- Nalmefene-d3 (CAS 55096-26-9 (Unlabeled))
Recommended Standards
- Bisoprolol Impurity 22 (CAS 1447715-45-8)
- Sacubitril Valsartan Sodium Impurity 2 (CAS 2806120-13-6)
- Tert-butyl 2-(1-hydroxy-2-tetrahydropyran-4-yl-ethyl)-3-oxo-8-azabicyclo[3.2.1]octane-8-carboxylate (CAS 2253686-83-6)
- tert-Butyl 2-(1-benzhydrylazetidin-3-yl)hydrazinecarboxylate (CAS 1025713-57-8)
- Teneligliptin Impurity 16 (CAS CATO-C4X-176016)
- Tofacitinib Impurity 179 HCl (CAS CATO-C4X-1079179)
- Bupropion Impurity 4 (CAS 376346-55-3)
- GSK-2269557 (CAS 1254036-77-5)
- 2-((2-Methoxybenzyl)amino)propan-1-ol (CAS 1154900-50-1)
- 5,6,7,8-Tetrahydro-1,8-naphthyridine-3-carboxylic acid (CAS 1023813-84-4)
- 5-Bromo-7-fluoro-1H-indol-3-amine (CAS 2758501-38-9)
- Fmoc-S-3-amino-4-(4-methoxyphenyl)-butyric acid (CAS 1352435-52-9)
- Methyl 5-Carboxy-N-phenyl-2-1H-pyridone (CAS 77837-09-3)
- Tau Peptide (295-309) trifluoroacetate salt (CAS 330456-46-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com