5-Ethyl-3-methylisoxazole-4-carbonyl chloride CAS 144272-76-4
| CAS No. | 144272-76-4 |
| Molecular Formula | C7H8ClNO2 |
| Molecular Weight | 173.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Ethyl-3-methylisoxazole-4-carbonyl chloride.
CATO supplies 5-Ethyl-3-methylisoxazole-4-carbonyl chloride (CAS 144272-76-4), a certified reference material (molecular formula C7H8ClNO2, MW 173.60 g/mol) for analytical method development and quality control.
Structurally, 5-Ethyl-3-methylisoxazole-4-carbonyl chloride (C7H8ClNO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 173.60 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Ethyl-3-methylisoxazole-4-carbonyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H8ClNO2 |
| Molecular Weight | 173.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
- 3-Ethyl-5-methylisoxazole-4-carbonyl chloride (CAS 99298-90-5)
- 3-Ethyl-5-methylisoxazole-4-carbohydrazide (CAS 1094733-72-8)
- 5-Methylisoxazole-3,4-dicarboxamide (CAS 400077-37-4)
- 3-Methylisoxazole-4-sulfonyl chloride (CAS 858489-87-9)
- 3-Butyl-5-methylisoxazole-4-carboxylic acid (CAS 1408451-86-4)
- Butyl 3-methylisoxazole-5-carboxylate (CAS 85153-59-9)
- Butyl 5-methylisoxazole-3-carboxylate (CAS 85168-94-1)
- 3-Methylisoxazole-4-sulfonic acid (CAS 747406-57-1)
Recommended Standards
- (3,5-dimethylisoxazol-4-yl)acetyl chloride (CAS 144102-13-6)
- 2-chloro-1-(dimethyl-1,3-oxazol-5-yl)ethan-1-one (CAS 1512604-21-5)
- (2-Chloro-4-(methylamino)pyrimidin-5-yl)methanol (CAS 1428760-93-3)
- 3-(Chloromethyl)-4H,6H,7H-pyrano[3,4-d][1,2]oxazole (CAS 1520052-11-2)
- Trichloroethyl Phosphate Cyclohexylamine (CAS 17331-54-3)
- 4-Bromo-3-(difluoromethyl)-2-fluoro-6-(trifluoromethyl)pyridine (CAS 1806903-73-0)
- 5-Methyl-5-(2-phenylethyl)imidazolidine-2,4-dione (CAS 5472-90-2)
- (S)-2-(Sec-butyl)-4,5-dihydrothiazole (CAS 250359-27-4)
- 3-Chloro-4-cyclohexylbenzoic acid (CAS 42601-80-9)
- N-METHYL-2-FLUORO-4-IODOBENZAMIDE (CAS 1351185-56-2)
- 4-Bromo-5-methylpyridazine (CAS 1368375-27-2)
- 2,2,2-Trifluoro-N-((3-phenylisoxazol-5-yl)methyl)acetamide (CAS 400087-16-3)
- 1-((4-Benzyl-4H-1,2,4-triazol-3-yl)methyl)piperazine (CAS 1707375-65-2)
- Anti-Inflammatory Peptide 2 (CAS 118850-72-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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