1-Ethoxy-2,3-difluoro-4-iodobenzene CAS 144292-42-2
| CAS No. | 144292-42-2 |
| Molecular Formula | C8H7F2IO |
| Molecular Weight | 284.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 1-Ethoxy-2,3-difluoro-4-iodobenzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
1-Ethoxy-2,3-difluoro-4-iodobenzene (CAS 144292-42-2), molecular formula C8H7F2IO and molecular weight 284.04 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a hydroxyl group, an ether linkage, fluorine/iodine substitution, an aromatic ring system, 1-Ethoxy-2,3-difluoro-4-iodobenzene is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 284.04 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H7F2IO |
| Molecular Weight | 284.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F/I-containing |
Related Ethoxy Standards
- 1-Ethoxy-4,5-difluoro-2-iodobenzene (CAS 2090513-06-5)
- 2-(5-Ethoxy-2,3-difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1445601-61-5)
- 2-(2-Ethoxy-3,4-difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2877757-14-5)
- 2-(3-Ethoxy-4,5-difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2121512-90-9)
- 2-(4-Ethoxy-2,3-difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2282635-46-3)
- 1-(Ethoxy(phenyl)phosphoryl)ethyl butyrate (CAS 866612-48-8)
- 3-{[4-(2-ethoxy-2-oxoethyl)-1,3-thiazol-2-yl]carbamoyl}prop-2-enoic acid (CAS 327105-83-9)
- 2-Ethoxy-4-formylphenyl 3-methylbenzoate (CAS 443647-58-3)
Recommended Standards
- 1-(Difluoromethoxy)-3-iodo-2-methylbenzene (CAS 1261825-62-0)
- (6-(2,5-Dimethyl-1H-pyrrol-1-yl)-4-(trifluoromethyl)pyridin-3-yl)boronic acid (CAS 2209066-06-6)
- 4-(Difluoromethoxy)-1-iodo-2-methylbenzene (CAS 1261678-37-8)
- 1-(2,6-Difluoro-3-iodophenyl)ethanol (CAS 2484889-28-1)
- 2-Cyano-N-(3-fluorophenyl)-3-(2-methoxyphenyl)acrylamide (CAS 312633-55-9)
- Diethyl 2-(amino(propylamino)methylene)malonate (CAS 40657-67-8)
- 5-Amino-2-chloro-3-methyl-6-(pyridin-4-yl)pyrimidin-4(3H)-one (CAS 831231-67-5)
- Ethyl 4,5-Difluoro-2-nitrobenzoate (CAS 1214387-06-0)
- 3-Bromo-2,4-dimethylphenol (CAS 74571-81-6)
- 2-Acetoxyphenylboronic Acid Pinacol Ester (CAS 480424-68-8)
- Cefathiamidine Impurity 4 (CAS 1418224-75-5)
- 4-((2-Fluoroethyl)amino)cyclohexan-1-ol (CAS 1866231-50-6)
- 5-Hydroxyquinoline-3-carbonitrile (CAS 1261577-22-3)
- [3-31]-Semaglutide D (CAS C152H230N42O47)
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