trans-3-fluoro-4-hydroxy-tetrahydropyran CAS 1443112-12-6
| CAS No. | 1443112-12-6 |
| Molecular Formula | C5H9FO2 |
| Molecular Weight | 120.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including trans-3-fluoro-4-hydroxy-tetrahydropyran.
trans-3-fluoro-4-hydroxy-tetrahydropyran (CAS 1443112-12-6), molecular formula C5H9FO2 and molecular weight 120.12 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of trans-3-fluoro-4-hydroxy-tetrahydropyran (C5H9FO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures trans-3-fluoro-4-hydroxy-tetrahydropyran under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H9FO2 |
| Molecular Weight | 120.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
Related trans Standards
- 3-Fluoro-3-methylbutanoic acid (CAS 1314982-17-6)
- 2-Fluoro-3-methylbutyric Acid (CAS 1578-62-7)
- 3-fluoro-2,2-dimethylpropanoic acid (CAS 64241-77-6)
- Methyl 2-Fluoro-2-methylpropionate (CAS 338-76-1)
- Methyl 3-fluoro-2-methylpropanoate (CAS 2253-38-5)
- 3-Fluoro-3-nitrooxetane (CAS 70187-44-9)
- trans-3-Fluoro-4-methoxypyrrolidine (CAS 1203566-98-6)
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Recommended Standards
- cis-3-fluorooxan-4-ol (CAS 1422188-18-8)
- 3-fluorooxan-4-ol (CAS 1481690-51-0)
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- [(3S)-3-fluorooxolan-3-yl]methanol (CAS 1268492-92-7)
- 3-Carboethoxy-2-piperidinomethyl benzophenone (CAS 898751-95-6)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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