4-(5-Nitrothiazol-2-yl)pyrazolidine-3,5-dione CAS 144316-58-5
| CAS No. | 144316-58-5 |
| Molecular Formula | C6H4N4O4S |
| Molecular Weight | 228.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(5-Nitrothiazol-2-yl)pyrazolidine-3,5-dione.
CATO supplies 4-(5-Nitrothiazol-2-yl)pyrazolidine-3,5-dione (CAS 144316-58-5), a certified reference material (molecular formula C6H4N4O4S, MW 228.19 g/mol) for analytical method development and quality control.
The molecular framework of 4-(5-Nitrothiazol-2-yl)pyrazolidine-3,5-dione (C6H4N4O4S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-(5-Nitrothiazol-2-yl)pyrazolidine-3,5-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H4N4O4S |
| Molecular Weight | 228.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Nitrothiazol Standards
- 3-Benzyl-5-nitrothiazol-2(3H)-imine (CAS 717814-25-0)
- N-(5-nitrothiazol-2-yl)furan-2-carboxamide (CAS 89899-03-6)
- 2-((5-Nitrothiazol-2-yl)amino)-2-oxoacetic acid (CAS 1448075-11-3)
- N-(5-Nitrothiazol-2-yl)-4,5-dihydrooxazol-2-amine (CAS 24240-60-6)
- 1-(5-Nitrothiazol-2-yl)pyrrolidin-2-one (CAS 13109-99-4)
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Recommended Standards
- Mono(carboxymethyl) Phthalate-d4 (CAS 1346600-11-0)
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- 4-(Cyclopropylmethoxy)-3,5-difluorobenzoic acid (CAS 1343436-42-9)
- Methyl 3-(3,4-difluorophenyl)-3-methyloxirane-2-carboxylate (CAS 1485337-68-5)
- (Z)-3-Chloro-N,N'-bis[(thiophen-2-yl)methyl]-5-(trifluoromethyl)pyridine-2-carboximidamide (CAS 338758-27-3)
- 4-Amino-3,7-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one (CAS 1260664-43-4)
- (3-Bromophenyl)(2-isopropylphenyl)methanol (CAS 1443333-24-1)
- 6-Bromo-2-chloropyridine-3-boronic acid (CAS 2121511-46-2)
- (1-Trityl-1H-imidazol-5-yl)methanol (CAS 172498-89-4)
- (4-Ethylfuran-3-yl)(phenyl)methanol (CAS 1248798-99-3)
- 4-Bromo-2-fluorothiophene (CAS 34746-38-8)
- 3-Hydroxyoctanoic Acid Methyl Ester (CAS 7367-87-5)
- 1,3-Bis(4-benzylpiperidin-1-yl)propane-1,3-dione (CAS 726152-94-9)
- C-Peptide 2 (rat) (CAS 41594-08-5)
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