3-(4-chlorophenyl)azetidine, trifluoroacetic acid CAS 1443238-27-4
| CAS No. | 1443238-27-4 |
| Molecular Formula | C9H10ClN |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 281.66 g/mol gives 3-(4-chlorophenyl)azetidine, trifluoroacetic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-(4-chlorophenyl)azetidine, trifluoroacetic acid (CAS 1443238-27-4), molecular formula C9H10ClNC2HF3O2 and molecular weight 281.66 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-(4-chlorophenyl)azetidine, trifluoroacetic acid (C9H10ClNC2HF3O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(4-chlorophenyl)azetidine, trifluoroacetic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H10ClN C2HF3O2 |
| Molecular Weight | 281.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related chlorophenyl Standards
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- N-(2-Chlorophenyl)-5-methyl-1-phenyl-1H-1,2,4-triazole-3-carboxamide (CAS 1000572-01-9)
- N-(2-Chlorophenyl)-5-oxo-1-(p-tolyl)-2,5-dihydro-1H-1,2,4-triazole-3-carboxamide (CAS 1000573-94-3)
- Methyl 1-(2-chlorophenyl)-2,5-dihydro-5-oxo-1H-1,2,4-triazole-3-carboxylate (CAS 1000576-85-1)
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- Benzyl 1-(4-chlorophenyl)-2,5-dihydro-5-oxo-1H-1,2,4-triazole-3-carboxylate (CAS 1000577-09-2)
- 1-(2-Chlorophenyl)-5-oxo-N-phenyl-2,5-dihydro-1H-1,2,4-triazole-3-carboxamide (CAS 1000577-29-6)
- 2-(2-Chlorophenyl)-1-phenylethan-1-amine (CAS 1000615-44-0)
Recommended Standards
- 2-Oxopropyl 4-bromobenzoate (CAS 900937-58-8)
- 2-Methoxy-5-(2-morpholinothiazol-4-yl)aniline (CAS 1443288-38-7)
- 2-Nitro-1-(3-nitrophenoxy)-4-(trifluoromethyl)benzene (CAS 500361-94-4)
- Oxacillin Impurity 9 (CAS CATO-C4X-23219)
- 3-Acetamido-5-chlorobenzenesulfonyl chloride (CAS 1310550-35-6)
- 2-(4-Methylpiperidin-1-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole (CAS 1356938-07-2)
- Methyl 1-isopropyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1160246-42-3)
- 4-((Diethylamino)methyl)aniline hydrochloride (CAS 1204811-84-6)
- n-(4-Fluoro-3-methylbenzyl)pentan-3-amine (CAS 1249685-68-4)
- Semaglutide impurity 65 (CAS CATO-C4X-222665)
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