1-Ethyl-3-(trifluoromethyl)-1H-pyrazol-4-amine hydrochloride CAS 1443279-48-8
| CAS No. | 1443279-48-8 |
| Molecular Formula | C6H8F3N3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-Ethyl-3-(trifluoromethyl)-1H-pyrazol-4-amine hydrochloride is closely related to a nitrile group, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 1-Ethyl-3-(trifluoromethyl)-1H-pyrazol-4-amine hydrochloride (CAS 1443279-48-8), a certified reference material (molecular formula C6H8F3N3HCl, MW 215.60 g/mol) for analytical method development and quality control.
Owing to a nitrile group, fluorine/chlorine substitution, 1-Ethyl-3-(trifluoromethyl)-1H-pyrazol-4-amine hydrochloride is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 215.60 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-Ethyl-3-(trifluoromethyl)-1H-pyrazol-4-amine hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H8F3N3 HCl |
| Molecular Weight | 215.60 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Ethyl Standards
- 3-(4-(Trifluoromethyl)phenyl)pyrrolidin-3-ol hydrochloride (CAS 1000198-74-2)
- 3-(4-(Trifluoromethyl)phenyl)pyrrolidine (CAS 1000198-76-4)
- (2-Methyl-4-(trifluoromethyl)thiazol-5-yl)methanol (CAS 1000339-72-9)
- methyl 3-((4-(trifluoromethyl)piperidin-1-yl)methyl)benzoate (CAS 1000339-86-5)
- methyl 4-(2-(4-(trifluoromethyl)piperidin-1-yl)ethoxy)benzoate (CAS 1000339-87-6)
- 2-(4-(trifluoromethyl)piperidin-1-yl)thiazole-5-carbaldehyde (CAS 1000339-88-7)
- 3-(2-(4-(trifluoromethyl)piperidin-1-yl)ethyl)benzaldehyde (CAS 1000339-89-8)
- 4-(2-(4-(trifluoromethyl)piperidin-1-yl)acetyl)-1H-pyrrole-2-carbaldehyde (CAS 1000339-90-1)
Recommended Standards
- 2-(4-Amino-3,5-dimethyl-1H-pyrazol-1-yl)propanoic acid hydrochloride (CAS 1431965-27-3)
- 5-(5-Bromothiophen-2-yl)isoxazol-3-amine (CAS 1267246-49-0)
- 1-((5-Bromo-2-methoxyphenyl)sulfonyl)-4-((tert-butyldiphenylsilyl)oxy)piperidine (CAS 1704081-03-7)
- Methyl 4-(pyrrolidin-3-yl)benzoate (CAS 1203797-98-1)
- 3-Bromo-4-(difluoromethoxy)phenylacetic Acid (CAS 2006277-18-3)
- 2-Bromo-1-(4-hydroxyphenyl)ethanone (CAS 168693-83-2)
- Diethyl Pentylmalonate (CAS 6065-59-4)
- (2-Bromophenyl)(4-chloro-2-methylphenyl)methanol (CAS 1443351-61-8)
- Ethyl 4-Hydroxy-8-(trifluoromethyl)-3-quinolinecarboxylate (CAS 23851-84-5)
- Tirzepatide Impurity 38 (CAS CATO-C4X-324038)
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