5-Bromo-2-methyl-6-(4-methylpiperazin-1-yl)nicotinic acid CAS 1443288-41-2
| CAS No. | 1443288-41-2 |
| Molecular Formula | C12H16BrN3O2 |
| Molecular Weight | 314.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Bromo-2-methyl-6-(4-methylpiperazin-1-yl)nicotinic acid.
5-Bromo-2-methyl-6-(4-methylpiperazin-1-yl)nicotinic acid (CAS 1443288-41-2), molecular formula C12H16BrN3O2 and molecular weight 314.18 g/mol, is a CATO reference standard with documented purity and traceability.
5-Bromo-2-methyl-6-(4-methylpiperazin-1-yl)nicotinic acid (C12H16BrN3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-Bromo-2-methyl-6-(4-methylpiperazin-1-yl)nicotinic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H16BrN3O2 |
| Molecular Weight | 314.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
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- 1-(3-Nitrophenyl)-1h-pyrazole-4-carbaldehyde (CAS 101872-31-5)
- Methyl 3-(difluoromethoxy)benzoate (CAS 773873-87-3)
- 1,4-dichloro-2,3-dihydro-1H-indene (CAS 1082562-97-7)
- (1S,3R)-3-(benzyloxy)-2,2-dimethylcyclobutan-1-ol (CAS 2059914-99-5)
- 6-Methoxyimidazo[1,5-a]pyridine-3-carbonitrile (CAS 2115633-50-4)
- Bromfenac Impurity 68 (CAS CATO-C4X-200268)
- (S)-2-Amino-5-hydroxy-4-oxopentanoic acid (CAS 26911-39-7)
- 1-Chloro-5-(chloromethyl)-2,4-difluorobenzene (CAS 1429422-43-4)
- (3as,7ar)-5,7-dibromo-3a-hydroxy-6-methoxy-3a,7a-dihydro-1-benzofuran-2(3h)-one 4361-28-8 KST-1A4839 (CAS 4361-28-8)
- Tirzepatide Impurity 44 (CAS CATO-C4X-324044)
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