2,2,2-Trifluoro-1-(4-isobutoxy-2,6-dimethylphenyl)ethan-1-one CAS 1443305-48-3
| CAS No. | 1443305-48-3 |
| Molecular Formula | C14H17F3O2 |
| Molecular Weight | 274.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2,2,2-Trifluoro-1-(4-isobutoxy-2,6-dimethylphenyl)ethan-1-one.
2,2,2-Trifluoro-1-(4-isobutoxy-2,6-dimethylphenyl)ethan-1-one (CAS 1443305-48-3), molecular formula C14H17F3O2 and molecular weight 274.28 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2,2,2-Trifluoro-1-(4-isobutoxy-2,6-dimethylphenyl)ethan-1-one (C14H17F3O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2,2,2-Trifluoro-1-(4-isobutoxy-2,6-dimethylphenyl)ethan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H17F3O2 |
| Molecular Weight | 274.28 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
Related Trifluoro Standards
- 2,2,2-Trifluoro-1-(3-methyl-4-(pentyloxy)phenyl)ethan-1-one (CAS 1443305-59-6)
- 2,2,2-Trifluoro-1-(4-(isopentyloxy)-2-methylphenyl)ethan-1-one (CAS 1443307-32-1)
- 2,2,2-Trifluoro-1-(2-methyl-4-(pentyloxy)phenyl)ethan-1-one (CAS 1443311-66-7)
- 2,2,2-Trifluoro-1-(2-(isopentyloxy)-5-methylphenyl)ethanone (CAS 1443311-68-9)
- 2,2,2-Trifluoro-1-(4-(isopentyloxy)-3-methylphenyl)ethan-1-one (CAS 1443344-36-2)
- 2,2,2-Trifluoro-1-(4-methyl-3-(pentyloxy)phenyl)ethan-1-one (CAS 1443344-68-0)
- 2,2,2-Trifluoro-1-(3-(isopentyloxy)-4-methylphenyl)ethan-1-one (CAS 1443349-47-0)
- 6,6,6-Trifluoro-5-hydroxy-2,2-dimethyl-5-phenylhexan-3-one (CAS 146801-16-3)
Recommended Standards
- 1-(4-Butoxy-2,6-dimethylphenyl)-2,2,2-trifluoroethan-1-one (CAS 1443305-42-7)
- 2-{4-[2-(trifluoromethyl)phenyl]piperazin-1-yl}ethan-1-ol (CAS 1432680-75-5)
- (1-(6-Nitroquinoxalin-2-yl)pyrrolidin-3-yl)methanol (CAS 1417794-35-4)
- 1-(6-Nitroquinoxalin-2-yl)piperidin-4-ol (CAS 1417793-14-6)
- 2,4-Dichloro-N-(4-((2-chlorophenyl)thio)phenyl)benzamide (CAS 339105-24-7)
- 1-(2,6-Dimethylpyrimidin-4-yl)pyrrolidin-3-ol (CAS 1338656-96-4)
- N-methyl-N-(6-methylpyridazin-3-yl)glycine (CAS 1083396-40-0)
- N-ethyl-3-fluoro-4-methylaniline hydrochloride (CAS 1909309-65-4)
- N-(2-Methoxyphenyl)-5-(2-(trifluoromethyl)phenyl)furan-2-carboxamide (CAS 622805-19-0)
- 1-(5-Bromo-2-methyl-3-(trifluoromethyl)phenyl)ethan-1-one (CAS 2383968-29-2)
- 4-Butoxy-2,3-difluorophenol (CAS 136239-68-4)
- N-(4-methylthiazol-2-yl)-1H-imidazole-1-carboxamide (CAS 1217486-99-1)
- 5-Bromo-2,4-difluoro-benzamide (CAS 1805583-56-5)
- Fragment-[3-31]-Liraglutide (CAS CATO-C4X-199232)
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