4-Fluoro-2-(piperidin-1-ylmethyl)benzenethiol CAS 1443305-74-5

Purity 97%+In StockPharmaceutical Standards
CAS No.1443305-74-5
Molecular FormulaC12H16FNS
Molecular Weight225.33 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-Fluoro-2-(piperidin-1-ylmethyl)benzenethiol CAS 1443305-74-5 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 225.33 g/mol gives 4-Fluoro-2-(piperidin-1-ylmethyl)benzenethiol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 4-Fluoro-2-(piperidin-1-ylmethyl)benzenethiol (CAS 1443305-74-5), a certified reference material (molecular formula C12H16FNS, MW 225.33 g/mol) for analytical method development and quality control.

4-Fluoro-2-(piperidin-1-ylmethyl)benzenethiol (C12H16FNS) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC12H16FNS
Molecular Weight225.33 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1992
Halogen ContentF-containing
Nitrogen Atoms1
Sulfur Atoms1

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