(4-Fluoro-3,5-dimethylphenyl)trimethylsilane CAS 1443311-41-8

Purity 97%+In StockPharmaceutical Standards
CAS No.1443311-41-8
Molecular FormulaC11H17FSi
Molecular Weight196.34 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(4-Fluoro-3,5-dimethylphenyl)trimethylsilane CAS 1443311-41-8 chemical structure

Description

CATO supplies (4-Fluoro-3,5-dimethylphenyl)trimethylsilane (CAS 1443311-41-8), a certified reference material (molecular formula C11H17FSi, MW 196.34 g/mol) for analytical method development and quality control.

The molecular framework of (4-Fluoro-3,5-dimethylphenyl)trimethylsilane (C11H17FSi) is characterized by fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC11H17FSi
Molecular Weight196.34 g/mol
Purity97%+
StorageStore at 2-8°C, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1992
Halogen ContentF-containing

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