(3,5-Bis(trifluoromethyl)phenyl)(thiazol-2-yl)methanone CAS 1443314-47-3
| CAS No. | 1443314-47-3 |
| Molecular Formula | C12H5F6NOS |
| Molecular Weight | 325.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (3,5-Bis(trifluoromethyl)phenyl)(thiazol-2-yl)methanone is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies (3,5-Bis(trifluoromethyl)phenyl)(thiazol-2-yl)methanone (CAS 1443314-47-3), a certified reference material (molecular formula C12H5F6NOS, MW 325.23 g/mol) for analytical method development and quality control.
(3,5-Bis(trifluoromethyl)phenyl)(thiazol-2-yl)methanone (C12H5F6NOS) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (3,5-Bis(trifluoromethyl)phenyl)(thiazol-2-yl)methanone under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H5F6NOS |
| Molecular Weight | 325.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Bis Standards
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Recommended Standards
- 2-(5-(4,5-Dimethoxy-2-nitrophenyl)-2-oxo-1,3,4-oxadiazol-3(2H)-yl)acetic acid (CAS 1216647-67-4)
- N-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propane-1-sulfonamide (CAS 1469930-91-3)
- [[2,2′-[1,2-Ethanediylbis(nitrilomethylidyne)]bis[phenolato-κO]](2-)]cobalt (CAS 1094215-76-5)
- N-Isopropyl-2-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide (CAS 1621520-78-2)
- Ganoderic acid F (CAS 98665-14-6)
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- 3-(4-bromothiophen-2-yl)-2-oxopropanoic acid (CAS 1155083-00-3)
- Ethyl 2-(4-bromophenyl)-3-hydroxy-2-(hydroxymethyl)propanoate (CAS 1423702-61-7)
- 1-(3-Fluorophenyl)-2-(1h-1,2,4-triazol-1-yl)ethan-1-one hydrochloride (CAS 1211113-09-5)
- 4-(Aminomethyl)-1H,2H,3H-pyrrolo[2,3-b]pyridin-2-one dihydrochloride (CAS 1818847-61-8)
- (11bR)-4-Phenoxy-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin (CAS 188055-47-2)
- Clenbuterol-d9 (CAS 129138-58-5)
- 2-(Methylsulfanyl)-7-[(Z)-2-(thiophen-2-yl)ethenyl]-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 339008-37-6)
- Pancreatic Polypeptide (31-36), amide, human (CAS 74012-13-8)
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