2,2,3,3,3-Pentafluoro-1-(4-methoxy-3,5-dimethylphenyl)propan-1-one CAS 1443314-51-9
| CAS No. | 1443314-51-9 |
| Molecular Formula | C12H11F5O2 |
| Molecular Weight | 282.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2,2,3,3,3-Pentafluoro-1-(4-methoxy-3,5-dimethylphenyl)propan-1-one is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2,2,3,3,3-Pentafluoro-1-(4-methoxy-3,5-dimethylphenyl)propan-1-one (CAS 1443314-51-9) is a high-purity analytical reference standard with the molecular formula C12H11F5O2 and a molecular weight of 282.21 g/mol.
The molecular framework of 2,2,3,3,3-Pentafluoro-1-(4-methoxy-3,5-dimethylphenyl)propan-1-one (C12H11F5O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2,2,3,3,3-Pentafluoro-1-(4-methoxy-3,5-dimethylphenyl)propan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H11F5O2 |
| Molecular Weight | 282.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
Related Pentafluoro Standards
- 2,2,3,3,3-Pentafluoro-1-(3-isopropoxyphenyl)propan-1-one (CAS 1443354-12-8)
- (2',3',4',5',6'-Pentafluoro-biphenyl-4-yl)-acetonitrile (CAS 893737-93-4)
- 4-(pentafluoro-$l^{6}-sulfanyl)benzene-1-sulfonamide (CAS 1461707-07-2)
- 4,4,5,5,5-Pentafluoro-1-(4-fluorophenyl)pentane-1,3-dione (CAS 64287-12-3)
- Methyl 3,3,4,4,4-pentafluoro-2-hydroxy-2-phenylbutanoate (CAS 723294-72-2)
- (E)-4,4,5,5,5-pentafluoro-1-((pyridin-3-ylmethyl)amino)pent-1-en-3-one (CAS 692738-21-9)
- 2,4,4,5,5-Pentafluoro-2-(trifluoromethyl)-1,3-oxathiolane-3,3-dioxide (CAS 26954-17-6)
- 1,2,3,4,5-pentafluoro-6-(trichloromethyl)benzene 1,2,3,4,5-pentakis(fluoranyl)-6-(trichloromethyl)benzene 778-34-7 A839211 (CAS 778-34-7)
Recommended Standards
- 1-(3,5-Difluoro-2-isobutoxyphenyl)-2,2,2-trifluoroethan-1-one (CAS 1443311-36-1)
- 1-(2-Butoxy-3,5-difluorophenyl)-2,2,2-trifluoroethanone (CAS 1443334-91-5)
- 3-Cyano-4-fluoro-n-(2,2,2-trifluoroethyl)benzene-1-sulfonamide (CAS 1394040-52-8)
- 1-(4-Butoxy-3,5-difluorophenyl)-2,2,2-trifluoroethan-1-one (CAS 1443344-05-5)
- 5-Cyclopropyl-1-ethyl-1H-pyrazol-3-amine (CAS 1172529-33-7)
- 5-(1-Methoxycyclopentyl)-1-methyl-1H-pyrazole-3-sulfonamide (CAS 2428478-79-7)
- 1,5-Dimethylpyrazole-4-boronic Acid Pinacol Ester (CAS 1036991-40-8)
- 2,4-Dimethyl-benzothiazole (CAS 5262-63-5)
- 4,7-Methanoisobenzofuran-1,3-dione, 3a,4,7,7a-tetrahydro-, homopolymer (CAS 55636-72-1)
- 2',6'-Dimethyl-[1,1'-biphenyl]-3,4',5-tricarboxylic acid (CAS 2270937-70-5)
- n-(3-Fluoro-2-methylphenyl)tetrahydro-2h-thiopyran-3-amine (CAS 1339596-41-6)
- 1-Methanesulfonylpiperidine-4-carbonitrile (CAS 438630-74-1)
- 5-[(isopropylamino)sulfonyl]-2-methylbenzoic acid (CAS 701272-37-9)
- (Glu1)-Fibrinopeptide B (human) (CAS 103213-49-6)
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