3,4-Difluoro-5-propoxybenzoic acid CAS 1443328-70-8
| CAS No. | 1443328-70-8 |
| Molecular Formula | C10H10F2O3 |
| Molecular Weight | 216.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3,4-Difluoro-5-propoxybenzoic acid (C10H10F2O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
3,4-Difluoro-5-propoxybenzoic acid (CAS 1443328-70-8), molecular formula C10H10F2O3 and molecular weight 216.18 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3,4-Difluoro-5-propoxybenzoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H10F2O3 |
| Molecular Weight | 216.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
Related Difluoro Standards
- Ethyl 3,5-difluoro-2-methoxybenzoate (CAS 1008138-31-5)
- 3-(3,5-Difluoro-4-methoxyphenyl)propanoic acid (CAS 105219-44-1)
- 3-(3,5-Difluoro-2-methoxyphenyl)propanoic acid (CAS 1092460-64-4)
- 3-(4,5-Difluoro-2-methoxyphenyl)propanoic acid (CAS 1092460-69-9)
- methyl 4-(2,2-difluoro-1-hydroxyethyl)benzoate (CAS 1176283-75-2)
- 2,4-Difluoro-3-(1-methylethoxy)benzoic acid (CAS 1219020-69-5)
- 2,3-Difluoro-6-nitro-n-propylaniline (CAS 1250052-21-1)
- Ethyl 3,4-difluoro-5-methoxybenzoate (CAS 1256469-95-0)
Recommended Standards
- Ethyl 2-(2,6-difluorophenoxy)acetate (CAS 1414144-27-6)
- 3,5-Difluoro-2-propoxybenzoic acid (CAS 1443344-16-8)
- 3-(2,6-Difluoro-4-methoxyphenyl)propanoic acid (CAS 1397193-35-9)
- 2-((2,3-Difluorophenoxy)methyl)-1,3-dioxolane (CAS 1443346-18-6)
- 1-(4-Methylpiperidin-1-yl)-3-(5-(3-nitrophenyl)furan-2-yl)prop-2-en-1-one (CAS 853351-51-6)
- (S)-N-(1-Hydroxy-3-(4-hydroxyphenyl)propan-2-yl)oleamide (CAS 616884-62-9)
- Methyl 1-methyl-6-nitro-1H-indazole-3-carboxylate (CAS 1058740-88-7)
- 4-(Aminomethyl)dihydrofuran-2(3h)-one (CAS 36679-82-0)
- Methyl (2-(4-(2-fluorophenyl)piperazin-1-yl)ethyl)carbamate (CAS 1208732-90-4)
- 3,3-bis (Methoxymethyl)-2-phenyl-1,3-dioxane (CAS 2209-91-8)
- Ethyl 2-bromo-8-hydroxyimidazo[1,2-b]pyridazine-7-carboxylate (CAS 1579103-55-1)
- 3-Methylpyrazole-4-carbaldehyde (CAS 112758-40-4)
- 6-Ethoxyspiro[benzo[e][1,3]oxazine-2,4'-piperidin]-4(3H)-one hydrochloride (CAS 1823188-30-2)
- Tirzepatide Impurity 49 (CAS CATO-C4X-324049)
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