2,2,2-Trifluoro-1-(3'-fluoro-[1,1'-biphenyl]-3-yl)ethan-1-one CAS 1443331-43-8

Purity 97%+In StockPharmaceutical Standards
CAS No.1443331-43-8
Molecular FormulaC14H8F4O
Molecular Weight268.21 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2,2,2-Trifluoro-1-(3'-fluoro-[1,1'-biphenyl]-3-yl)ethan-1-one CAS 1443331-43-8 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 268.21 g/mol gives 2,2,2-Trifluoro-1-(3'-fluoro-[1,1'-biphenyl]-3-yl)ethan-1-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2,2,2-Trifluoro-1-(3'-fluoro-[1,1'-biphenyl]-3-yl)ethan-1-one (CAS 1443331-43-8), molecular formula C14H8F4O and molecular weight 268.21 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2,2,2-Trifluoro-1-(3'-fluoro-[1,1'-biphenyl]-3-yl)ethan-1-one (C14H8F4O) is characterized by a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 2,2,2-Trifluoro-1-(3'-fluoro-[1,1'-biphenyl]-3-yl)ethan-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC14H8F4O
Molecular Weight268.21 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1992
Halogen ContentF-containing

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